Peripheral Arterial Disease Clinical Trials

88 recruiting

Peripheral Arterial Disease Trials at a Glance

95 actively recruiting trials for peripheral arterial disease are listed on ClinicalTrialsFinder across 6 cities in 41 countries. The largest study group is Not Applicable with 42 trials, with the heaviest enrollment activity in Cleveland, Omaha, and Chicago. Lead sponsors running peripheral arterial disease studies include University of Nebraska, EndoCore Lab s.r.l., and Baylor Research Institute.

Browse peripheral arterial disease trials by phase

Treatments under study

About Peripheral Arterial Disease Clinical Trials

Looking for clinical trials for Peripheral Arterial Disease? There are currently 88 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Peripheral Arterial Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Peripheral Arterial Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 95 trials

Recruiting
Not Applicable

Handgrip Training in Patients With Peripheral Artery Disease

Peripheral Arterial Disease
University of Nove de Julho30 enrolled2 locationsNCT03663777
Recruiting
Not Applicable

SELUTION4BTK Trial

Peripheral Arterial DiseaseChronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
M.A. Med Alliance S.A.376 enrolled48 locationsNCT05055297
Recruiting
Not Applicable

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

Peripheral Arterial Disease
University of Tennessee Graduate School of Medicine81 enrolled1 locationNCT07223437
Recruiting
Phase 2

A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease

Peripheral Arterial DiseaseCoronary Artery Disease (CAD)
Sirius Therapeutics Co., Ltd.104 enrolled1 locationNCT07318155
Recruiting
Phase 3

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Peripheral Arterial Disease
Eli Lilly and Company1,205 enrolled138 locationsNCT07223593
Recruiting
Phase 3

SMART Exercise for PAD

Peripheral Arterial DiseaseAgingWalking, Difficulty+1 more
Northwestern University210 enrolled3 locationsNCT06032065
Recruiting
Phase 2

Fisetin to Reduce Senescence and Mobility Impairment in PAD

ClaudicationPeripheral Arterial DiseaseAging+2 more
Northwestern University34 enrolled1 locationNCT06399809
Recruiting
Phase 4

Vascular Trial Associated Registry Pilot

Peripheral Arterial Disease
Corewell Health West350 enrolled2 locationsNCT07076082
Recruiting
Not Applicable

EVERO Drug-coated Balloon (DCB) Randomized Trial

Peripheral Arterial DiseasePeripheral Vascular Disease
Cook Research Incorporated410 enrolled1 locationNCT07144150
Recruiting

Tele-assessment and Face-to-face Assessment of the 30-second Sit-stand Test in Peripheral Artery Disease

Peripheral Arterial Disease
Izmir Democracy University45 enrolled1 locationNCT07497360
Recruiting

Peripheral Extreme Revascularization in "No-option" Patiens With Chronic Limb Threatening Ischemia

Peripheral Arterial DiseaseDiabetic FootCritical Limb-Threatening Ischemia
EndoCore Lab s.r.l.50 enrolled9 locationsNCT06277362
Recruiting

Use of Shockwave M5+/L6 IVL Catheter (Intravascular Lithotripsy) in Hostile and Calcified Iliac Access

Peripheral Arterial DiseaseAortic DiseasesAorto-Iliac Atherosclerosis
EndoCore Lab s.r.l.40 enrolled6 locationsNCT05880641
Recruiting
Not Applicable

The Efemoral Vascular Scaffold System (EVSS) for the Treatment of Patients With Symptomatic Peripheral Vascular Disease From Stenosis or Occlusion of the Femoropopliteal Artery

Peripheral Arterial DiseaseStenosisVascular Diseases+1 more
Efemoral Medical, Inc.100 enrolled8 locationsNCT04584632
Recruiting
Phase 3

Low Dose ColchicinE in pAtients With Peripheral Artery DiseasE to Address Residual Vascular Risk

Peripheral Arterial DiseaseInflammationAtherosclerosis of Extremities
Population Health Research Institute6,150 enrolled70 locationsNCT04774159
Recruiting

Vascular Complications in Patients Undergoing Peripheral Revascularization and Taking SGLT-2 Inhibitors

Peripheral Arterial Disease(PAD)
Wroclaw Medical University300 enrolled1 locationNCT07157475
Recruiting
Not Applicable

Intravascular Ultrasound Imaging Guidance for Optimal Revascularization of Limb Arteries

Peripheral Arterial DiseaseLower Extremity Arterial Disease
Baylor Research Institute350 enrolled6 locationsNCT07353905
Recruiting

Symptomatic and Systemic Atherosclerotic Plaque Activity in Patients With Peripheral Arterial Disease Using Novel Imaging

Peripheral Arterial DiseaseChronic Limb Threatening Ischemia
University of Edinburgh100 enrolled1 locationNCT07472049
Recruiting

Intervascular Post-Market Clinical Follow-Up (PMCF) Registry

Aortic DiseasesCarotid Artery DiseasesPeripheral Arterial Diseases
Intervascular1,200 enrolled3 locationsNCT07322913
Recruiting

Advanta VXT and Flixene PMCF Registry

Peripheral Arterial Disease
Atrium Medical Corporation1,000 enrolled2 locationsNCT07161583
Recruiting

VITUS Post-Market Registry

Peripheral Arterial Disease
OrbusNeich284 enrolled13 locationsNCT06832631