Peripheral Arterial Disease Clinical Trials

104 recruitingLast updated: June 17, 2026

There are 104 actively recruiting peripheral arterial disease clinical trials across 41 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include Cleveland, Ohio, United States, Boston, Massachusetts, United States, Gainesville, Florida, United States. Updated daily from ClinicalTrials.gov.


Peripheral Arterial Disease Trials at a Glance

104 actively recruiting trials for peripheral arterial disease are listed on ClinicalTrialsFinder across 6 cities in 41 countries. The largest study group is Not Applicable with 47 trials, with the heaviest enrollment activity in Cleveland, Boston, and Gainesville. Lead sponsors running peripheral arterial disease studies include University of Nebraska, EndoCore Lab s.r.l., and Baylor Research Institute.

Browse peripheral arterial disease trials by phase

Treatments under study

About Peripheral Arterial Disease Clinical Trials

Looking for clinical trials for Peripheral Arterial Disease? There are currently 94 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Peripheral Arterial Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Peripheral Arterial Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 104 trials

Recruiting

Intervascular Post-Market Clinical Follow-Up (PMCF) Registry

Aortic DiseasesCarotid Artery DiseasesPeripheral Arterial Diseases
Intervascular1,200 enrolled4 locationsNCT07322913
Recruiting
Not Applicable

Examining the Use of Three Dimensional Ultrasound in the Assessment of Vascular Pathologies

WoundsVascular DiseasesPAD - Peripheral Arterial Disease
Northwell Health270 enrolled1 locationNCT05134311
Recruiting

Case-Specific Health Care Professional Clinical Survey of Liberant™ Thrombectomy System

Peripheral Arterial DiseaseDVTAcute Limb Ischemia+8 more
Medtronic Endovascular50 enrolled2 locationsNCT07335341
Recruiting
Not Applicable

The Golazo® Peripheral Atherectomy System for a Safe and Effective Atherectomy (GREAT Trial)

Peripheral Arterial Disease
Avantec Vascular159 enrolled20 locationsNCT06321575
Recruiting
Not Applicable

EVERO Drug-coated Balloon (DCB) Randomized Trial

Peripheral Arterial DiseasePeripheral Vascular Disease
Cook Research Incorporated410 enrolled3 locationsNCT07144150
Recruiting
Not Applicable

Intravascular Ultrasound for Peripheral Artery Disease Revascularization

Chronic Limb Threatening IschemiaPeripheral Arterial Disease(PAD)Restenosis+2 more
Hamilton Health Sciences Corporation772 enrolled2 locationsNCT06979284
Recruiting
Phase 1

The Pharmacokinetics and Pharmacodynamics Study of CG-0255 Besylate and Plavix® in Healthy Participants

Peripheral Arterial DiseaseRecent Myocardial InfarctionRecent Stroke+1 more
Shanghai CureGene Pharmaceutical Co., Ltd.136 enrolled1 locationNCT07619885
Recruiting
Phase 3

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Peripheral Arterial Disease
Eli Lilly and Company1,205 enrolled138 locationsNCT07223593
Recruiting

Radial Access Data in Vascular Interventions Registry

Peripheral Arterial DiseaseCoronary Artery DiseaseRadial Artery Spasm+2 more
Mersin Medicalpark Hastanesi20,000 enrolled1 locationNCT07614386
Recruiting
Not Applicable

Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease

ThrombosisAmputationPlatelet Aggregation Inhibitors+4 more
Massachusetts General Hospital484 enrolled2 locationsNCT07613840
Recruiting
Not Applicable

The GORE VBX FORWARD Clinical Study: A Comparison of the GORE® VIABAHN® VBX Balloon Expandable Endoprosthesis to Bare Metal Stenting for Patients With Complex Iliac Occlusive Disease

Aortoiliac occlusive diseasePeripheral Arterial Disease
W.L.Gore & Associates244 enrolled43 locationsNCT05811364
Recruiting
Not Applicable

Comparison of a Lithotripsy vs Standard Preparation Followed by Stenting With Supera Stent in Femoropopliteal Lesions

Peripheral Arterial Disease
University of Leipzig120 enrolled1 locationNCT06112171
Recruiting
Not Applicable

Ultrasound Perfusion Estimation for Assessment of Peripheral Arterial Disease

Peripheral Arterial Disease
Mayo Clinic400 enrolled1 locationNCT06952543
Recruiting
Not Applicable

Handgrip Training in Patients With Peripheral Artery Disease

Peripheral Arterial Disease
University of Nove de Julho30 enrolled2 locationsNCT03663777
Recruiting
Not Applicable

SELUTION4BTK Trial

Peripheral Arterial DiseaseChronic Limb-Threatening Ischemia Nos of Native Arteries of Extremities
M.A. Med Alliance S.A.376 enrolled48 locationsNCT05055297
Recruiting
Not Applicable

REVASC-PAD: REstricted VASCular Exercise for Peripheral Arterial Disease - A Feasibility Study at University of Tennessee Medical Center

Peripheral Arterial Disease
University of Tennessee Graduate School of Medicine81 enrolled1 locationNCT07223437
Recruiting
Phase 2

A Study of SRSD107 in Participants With Chronic Coronary and/or Peripheral Arterial Disease

Peripheral Arterial DiseaseCoronary Artery Disease (CAD)
Sirius Therapeutics Co., Ltd.104 enrolled1 locationNCT07318155
Recruiting
Not Applicable

PROMISE III: Percutaneous Deep Vein Arterialization for the Treatment of Late-Stage Chronic Limb-Threatening Ischemia

Peripheral Arterial DiseaseChronic Limb Threatening IschemiaCritical Limb Ischemia
LimFlow, Inc.100 enrolled30 locationsNCT05313165
Recruiting
Phase 2

Fisetin to Reduce Senescence and Mobility Impairment in PAD

ClaudicationPeripheral Arterial DiseaseAging+2 more
Northwestern University34 enrolled1 locationNCT06399809
Recruiting
Phase 3

SMART Exercise for PAD

Peripheral Arterial DiseaseAgingWalking, Difficulty+1 more
Northwestern University210 enrolled3 locationsNCT06032065