RecruitingNot ApplicableNCT06214598

Anti-Inflammatory Diet in BRC Patients on Aromatase Inhibitors

Anti-Inflammatory Dietary Intervention in Breast Cancer Patients Receiving Aromatase Inhibitors


Sponsor

University of Belgrade

Enrollment

90 participants

Start Date

Mar 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This project aims to decrease undesirable side effects and increase qulaity of life of aromatase inhibitors therapy in breast cancer survivors, by anti-inflammatory diet or supplementation.


Eligibility

Sex: FEMALEMin Age: 45 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing whether an anti-inflammatory diet can help reduce joint pain and other side effects in postmenopausal women with breast cancer who are taking aromatase inhibitors (hormone-blocking medications used after breast cancer treatment). Aromatase inhibitors commonly cause joint stiffness and pain, and the study wants to see if diet can help. **You may be eligible if...** - You are 45 to 70 years old and postmenopausal - You have been diagnosed with hormone receptor-positive, HER2-negative breast cancer (stages I to IIIa) - You have been taking aromatase inhibitors for 6 to 30 months - Your BMI is between 20 and 34.9 - You are able to understand the study and give written consent **You may NOT be eligible if...** - Your breast cancer has spread or is locally advanced - Your tumor is HER2-positive - You have another serious chronic illness, active infection, autoimmune disease, or a history of stroke or heart attack - You have dementia or a significant neurological condition - You have allergies to fish, fish oil, nuts, or evening primrose oil - You are currently taking blood-thinning medications like warfarin - You are currently using fish oil, flaxseed, or omega-3 supplements - You take cholesterol-lowering medications (statins) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTSupplement

Supplements of anti-inflammatory oils rich in omega-3 and gamma-linolenic acid

DIETARY_SUPPLEMENTAI diet

diet rich in whole grains, healthy oils and polyphenols,

DIETARY_SUPPLEMENTPlacebo

Placebo caps with standard diet


Locations(2)

Clinical Hospital Center Bezanijska kosa

Belgrade, Serbia

Center of Research Excellence in Nutrition and Metabolism, Institute for Medical Research, University of Belgrade

Belgrade, Serbia

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NCT06214598


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