RecruitingNot ApplicableNCT06215326

Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients

Short-term Effects of Preoperative Exercise in Moderate-to-high Perioperative Risk Lung Cancer Patients(PRE-EXELUCA): a Prospective Randomized Controlled Clinical Trial


Sponsor

Guangdong Provincial People's Hospital

Enrollment

100 participants

Start Date

Jan 23, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trail is to compare the effects of preoperative exercise training of different intensities on short-term cardiorespiratory function and postoperative outcomes in patients scheduled for lung resections.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial is studying the short-term benefits of a structured exercise program in the weeks before lung cancer surgery for patients who are at higher risk of complications. Getting fitter before major surgery — sometimes called "prehabilitation" — may help people recover faster and have fewer complications. This study focuses on patients whose lung function or fitness is below the usual safe threshold for surgery. **You may be eligible if...** - You are over 18 years old - You have suspected or confirmed lung cancer with surgery planned - You are considered moderate to high risk for surgery complications based on breathing tests or fitness measurements - You can complete a full cardiopulmonary exercise test (a test measuring how your heart and lungs perform during physical activity) **You may NOT be eligible if...** - You have had or currently have another type of cancer - Your life expectancy is less than 1 year - You have dementia or physical limitations that prevent you from exercising - You have abnormal vital signs at rest (very fast or slow heart rate, very high blood pressure, low oxygen levels, or fever) - You are enrolled in another clinical trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALmoderate-intensity continuous training

Each MICT session consists of 30 minutes of cycling. Workload will be gradually titrated from 50% to 60% peak WR throughout training to sustain a target RPE of 12-14 on the Borg 6-20 scale.

BEHAVIORALhigh-intensity interval training

Each HIIT session consists of15 cycles, includes a 60-second high-intensity interval at 80-95% peak WR (target RPE 15-17) followed by a 60-second active recovery phase at 25% peak WR.


Locations(1)

Guangdong Provincial People's Hospital

Guangzhou, Guangdong, China

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NCT06215326


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