RecruitingNot ApplicableNCT06216964
Time to Clearance of Chlamydia Trachomatis and Neisseria Gonorrhoeae RNA After Treatment: a Prospective Cohort Study
Sponsor
University Hospital, Strasbourg, France
Enrollment
140 participants
Start Date
Apr 5, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
The aim of this study is to evaluate the negativation time of chlamydial and gonococcal PCRs after treatment for urogenital, oropharyngeal and anal infections.
Eligibility
Min Age: 18 Years
Inclusion Criteria6
- \- Patients attending the Trait d'Union department at the Nouvel Hôpital Civil for PrEP consultations, AES or HIV infection.
- Over 18 years of age
- Male or female
- Who have had an uncomplicated CT and/or NG infection treated with currently recommended therapies (Ceftriaxone 500mg DU for NG infections, Doxycycline 200mg per day for 1 week for rectal CT infections and Azithromycin 1g DU or Doxycycline 7 days for other CT infections).
- Subject affiliated to a social health insurance scheme
- Subject able to understand the aims and risks of the research and to give dated and signed informed consent
Exclusion Criteria5
- \- Complicated CT and/or NG infections: epididymitis, prostatitis, upper genital infection, extra-genital involvement (keratoconjunctivitis, arthritis, skin involvement, Fiessinger-Leroy-reiter syndrome, Fitz-Hugh-Curtis syndrome).
- Interfering treatments and associated diseases: Severe immunosuppression (HIV infection with CD4 less than 200/mm3, chemotherapy in the last 6 months, active haemopathy, congenital immune deficiency, immunosuppressive treatment including corticosteroid therapy for more than 4 weeks or organ transplant.
- Impossibility of giving the subject informed information (subject in an emergency situation, difficulties in understanding the subject, etc.).
- Subject under court protection
- Subject under guardianship or curatorship
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Interventions
DIAGNOSTIC_TESTChlamydia trachomatis (CT) and/or Neisseria gonorrhoeae (NG) NAAT(s)
Test every week after the start of treatment, until NAAT negativation and up to a maximum of 4 weeks
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06216964