RecruitingNot ApplicableNCT06217276

Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation

Examining the Relationship Between Respiratory Muscle Fatigue and Lower Extremity Muscle Oxygenation in Chronic Obstructive Pulmonary Disease Patients.

Sponsor

Istanbul Medipol University Hospital

Enrollment

30 participants

Start Date

Jan 20, 2024

Study Type

INTERVENTIONAL

Conditions

COPD

Summary

In our study, changes in vastus lateralis muscle oxygenation will be evaluated with the Moxy device, a functional infrared oxygen measurement device, during the inspiratory muscle fatigue protocol in COPD cases and the healthy control group.

Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at how the breathing muscles and leg muscles perform and use oxygen during exercise in patients with chronic lung disease (COPD). The researchers want to understand how respiratory muscle fatigue relates to reduced blood flow and oxygen delivery to the legs during physical activity. **You may be eligible if...** - You have been diagnosed with COPD or another chronic respiratory condition - You are 18 or older - You are able to perform exercise testing on a stationary bike - You are medically stable enough to participate in exercise testing **You may NOT be eligible if...** - You have a condition that prevents safe exercise testing (e.g., unstable heart disease) - You are currently experiencing a flare-up of your lung condition - You are unable to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERRespiratory muscle fatigue protocol

It will be performed using a powerbreath device at 60% of the maximum inspiratory pressure (MIP) amount obtained by measuring mouth pressure. The protocol includes 7 sets consisting of 2 minutes of inspiratory effort and 1 minute of rest. To further confirm the occurrence of fatigue, the patient will score fatigue using the modified Borg scale, and the score will be 5 or above11. During the application, heart rate, blood pressure and peripheral oxygen saturation will be monitored. The measurement will be performed once for each case.