A Study of HRS9531 in Participants With Impaired Kidney Function and Healthy Subjects

This study is looking at how a drug called HRS9531 — which belongs to a class of diabetes and obesity medications called GLP-1/GIP receptor agonists — behaves in the body (how it is absorbed, broken down, and eliminated) in people with varying degrees of kidney function. This pharmacokinetics study is an important safety step before the drug can be more widely tested. **You may be eligible if...** - You are between 18 and 65 years old - Your body mass index (BMI) is between 19 and 40 - You fall into one of five kidney function categories: normal, mild impairment, moderate impairment, severe impairment, or end-stage kidney failure (on dialysis) - Women who could become pregnant must use effective contraception and test negative for pregnancy **You may NOT be eligible if...** - You have a history of serious allergic reactions to similar GLP-1 medications - You have personal or family history of thyroid cancer (specifically medullary thyroid carcinoma) or a rare endocrine tumor syndrome (MEN2) - You have uncontrolled diabetes or other serious metabolic conditions - You are pregnant, breastfeeding, or planning pregnancy during the study Talk to your doctor to see if this trial is right for you.