Left Roof Linear, Mitral Isthmus Linear and Left Anterior Septal Linear Ablation for Non-paroxysmal AF: PROMISED Trial.

This study tests a type of heart procedure called catheter ablation with additional "line" burns inside the left atrium to treat persistent atrial fibrillation (an irregular heart rhythm lasting more than 7 days) in patients who are at high risk of stroke but either cannot or will not take blood thinners long-term. **You may be eligible if...** - You are over 18 years old - You have persistent atrial fibrillation lasting more than 7 days - You have a stroke risk score of 2 or more (CHA2DS2-VASc ≥2) - You are unable to take long-term blood thinners, or had a stroke despite being on them, or have a high bleeding risk, or simply do not want to take them long-term **You may NOT be eligible if...** - You have had a previous atrial fibrillation ablation procedure - Your left atrium is very enlarged (over 60mm) - Your AF has persisted for more than 10 years - You have a blood clot in your heart - You are scheduled for heart surgery Talk to your doctor to see if this trial is right for you.