Atrial Fibrillation, Persistent Clinical Trials

12 recruiting

Frequently Asked Questions

Common questions about Atrial Fibrillation, Persistent clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

Hybrid Ablation of Atrial Fibrillation in Heart Failure

Heart FailureAtrial FibrillationAtrial Arrhythmia+3 more
St. George's Hospital, London120 enrolled7 locationsNCT05411614
Recruiting
Not Applicable

Atrioventricular Node Ablation and Conduction System Pacing in Patients With Well Controlled Permanent Atrial Fibrillation (AF), Heart Failure and Preserved Ejection Fraction: Heart Rate Regularization Versus Medical Rate Control

Heart Failure With Preserved Ejection FractionAtrial Fibrillation, Persistent
French Cardiology Society266 enrolled15 locationsNCT06833138
Recruiting
Not Applicable

Value of Screening and Treatment of SAHS in the Management of AF Ablation Candidates

Atrial Fibrillation, PersistentAtrial Fibrillation (Paroxysmal)Apnea Syndrome+1 more
Hospital San Carlos, Madrid50 enrolled1 locationNCT04606693
Recruiting
Not Applicable

Convergent Ablation Plus Left Atrial Appendage Isolation for the Treatment of Persistent Atrial Fibrillation

Atrial ArrhythmiaPersistent Atrial FibrillationAtrial Fibrillation, Persistent+1 more
Barts & The London NHS Trust48 enrolled1 locationNCT06165510
Recruiting
Not Applicable

Electrical Cardioversion As a Predictor in Postoperative Preservation of Sinus Rhythm

Atrial FibrillationAtrial Fibrillation, Persistent
Saint Petersburg State University, Russia125 enrolled1 locationNCT06654401
Recruiting
Not Applicable

Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure

Heart FailureAtrial Fibrillation, Persistent
University Hospital, Geneva220 enrolled18 locationsNCT06207383
Recruiting
Not Applicable

Optimal Pacing Rate for Cardiac Resynchronization Therapy

Atrial Fibrillation, Persistent
Medstar Health Research Institute60 enrolled5 locationsNCT06445439
Recruiting
Not Applicable

Comparison of Catheter Plus Marshall Vein Ablation vs. Catheter Ablation Alone in Persistent AF With Heart Failure

Heart FailureAtrial Fibrillation, Persistent
Second Xiangya Hospital of Central South University120 enrolled1 locationNCT06578793
Recruiting
Not Applicable

Ablation of Focal Activation in Atrial Fibrillation

Atrial FibrillationArrhythmias, CardiacArrhythmia+2 more
Imperial College London110 enrolled1 locationNCT06402617
Recruiting

In-depth Characterization of Atriogenic Secondary Tricuspid Regurgitation Due to Atrial Fibrillation

Atrial Fibrillation, PersistentHeart Valve Incompetence
Istituto Auxologico Italiano1,050 enrolled2 locationsNCT05749107
Recruiting
Not Applicable

Left Roof Linear, Mitral Isthmus Linear and Left Anterior Septal Linear Ablation for Non-paroxysmal AF: PROMISED Trial.

Atrial FibrillationAtrial Fibrillation, Persistent
Second Affiliated Hospital of Wenzhou Medical University166 enrolled1 locationNCT06249347
Recruiting
Not Applicable

Thoracoscopic Surgical Versus Catheter Ablation Approaches for Primary Treatment of Persistent Atrial Fibrillation

Atrial Fibrillation, Persistent
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)170 enrolled3 locationsNCT04715425