RecruitingNCT06263868

First Observatory of Precocious Puberty.

First Observatory of Precocious and Advanced Puberty in Private Healthcare.


Sponsor

Hospices Civils de Lyon

Enrollment

3,360 participants

Start Date

Jun 26, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The age of puberty has fluctuated throughout history. Recent data shows an increase in the age of onset of puberty signs, in the United States but also in Europe. A recent Public Health France study published in 2018 reports an increase in the incidence of precocious puberty with geographical heterogeneity. The consequences of these appearances include the early onset of menarche, short adult height and the psychological impact. Due to a lack of studies and additional data, the reasons for this development are difficult to understand. Among current hypotheses, the entanglement with the evolution of our environment is at the forefront: the action of environmental endocrine disruptors and nutritional factors could play a role in the process of early appearance of pubertal signs. The establishment of a national observatory for early and advanced puberty in collaboration with pediatric endocrinologists (on the front line) would allow a reliable and precise field approach, capable of supplementing epidemiological data, which are currently insufficient. The investigators hypothesize that the establishment of an observatory of pubertal advances (early puberty and advanced puberty) in private medicine is possible, with inclusion of at least 75% of eligible patients, and collection of at least 80% of data.


Eligibility

Max Age: 11 Years

Inclusion Criteria10

  • Precocious puberty group (PP) :
  • Suspected precocious puberty (girl aged \< 8 years or boy aged \< 9 years when the first signs of development\* appear)
  • Suspected precocious puberty (girl aged \< 8 years or boy aged \< 9 years when the first signs of development\* appear)
  • Advanced puberty group (AP) :
  • Suspected advanced puberty (girl aged ≥ 8 and \< 10 years or boy aged ≥ 9 and \< 11 years when the first signs of development\* appear)
  • First consultation with the investigator (pediatric endocrinologist).
  • Control group :
  • Boy or girl without signs of pubertal development (Tanner 1);
  • Matched to the PP group on sex and age (+/- 1 year);
  • Consultation with the same investigator over the same period (same quarter) as a patient in the PP group

Exclusion Criteria3

  • All groups
  • Consultation with the same investigator over the same period (same quarter) as a patient in the PP group
  • Family not speaking French, language barrier.

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Locations(25)

Clinique du Val d'Ouest

Écully, Auvergne-Rhône-Alpes, France

Clinique du Val d'Ouest

Écully, Auvergne-Rhône-Alpes, France

Clinique du Val d'Ouest

Écully, Auvergne-Rhône-Alpes, France

Pediatric practice

Lyon, Auvergne-Rhône-Alpes, France

Pediatric practice

Rennes, Brittany Region, France

Pediatric practice

Chambray-lès-Tours, Centre-Val de Loire, France

Pediatric practice

Essey-lès-Nancy, Grand Est, France

Pediatric practice

Levallois-Perret, Hauts-de-Seine, France

Pediatric practice

Fondettes, Indre-et-Loire, France

Polyclinique Bordeaux rive droite

Lormont, Nouvelle-Aquitaine, France

Pediatric practice

Pau, Nouvelle-Aquitaine, France

Pediatric Practice

Pessac, Nouvelle-Aquitaine, France

Clinique rive gauche

Toulouse, Occitanie, France

Pediatric practice

Saint-Nazaire, Pays de la Loire Region, France

Pediatric practice

Aix-en-Provence, France

Hôpital Femme Mère Enfant, Hospices civils de Lyon

Bron, France

Pediatric practice

Marseille, France

Pediatric practice

Marseille, France

Pediatric practice

Nice, France

Clinique Saint jean

Saint-Jean-de-Védas, France

Pediatric practice

Trélazé, France

Pediatric practice

Paris, Île-de-France Region, France

Pediatric practice

Paris, Île-de-France Region, France

Pediatric practice

Paris, Île-de-France Region, France

Pediatric practice

Paris, Île-de-France Region, France

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