RecruitingNCT04884620

The 3rd COPENHAGEN Puberty Study

The COPENHAGEN School Study. Normal Pubertal Development in Youth 2021 and Long-term Disease and Death Risk After Extremely Early Puberty


Sponsor

Rigshospitalet, Denmark

Enrollment

3,000 participants

Start Date

Jan 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The COPENHAGEN School Study is a combined cross-sectional and longitudinal study of healthy Danish school children. This study will by clinical examinations and withdrawal of blood samples investigate whether age of pubertal onset is continuing to decline in Denmark over the past 15 years. Furthermore, we will investigate the mechanism driving earlier onset of puberty and the long term health risks of extremely early puberty using Danish registry data


Eligibility

Min Age: 5 YearsMax Age: 19 Years

Inclusion Criteria1

  • Healthy children and adolescents

Exclusion Criteria2

  • In case of acute disease, cancer, cancer therapy, or chronic disease (History of malignant disease, chemotherapy or radiation, cystic fibrosis, juvenile rheumatoid arthritis, systemic lupus erythematosus, sickle cell disease, thalassemia, chronic renal disease or known numerical chromosome aberration)
  • Non-Caucasian

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Locations(1)

Rigshospitalet, Department of Growth and Reproduction

Copenhagen, Denmark

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NCT04884620


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