RecruitingNot ApplicableNCT06269679

CBCT vs OPT on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocarditis.

3D Imaging (Cone Beam Computed Tomography) Versus Orthopantomogram on the Oral Health Status at 12 Months of Patients Hospitalized for Infective Endocarditis: a Multicenter Randomized Superiority Controlled Trial.


Sponsor

Nantes University Hospital

Enrollment

170 participants

Start Date

Dec 18, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

1\. Infective Endocarditis (IE) is a rare and serious disease with high morbidity and mortality; 2. Streptoccoci of oral origin are the second more frequent microorganisms responsible for IE; 3. Oral Infectious Foci (OIF) are underdetected using the current recommended clinical examination/Orthopantomogram (OPT) approach; 4. Cone Beam Computed Tomography (CBCT) has a better sensitivity and sensibility to detect OIF than OPT; 5. To date, no study has been performed to assess the potential benefit of a clinical examination/CBCT approach on the oral health status in IE patients. Thus, conducting a randomized controlled trial is highly desirable to assess the potential impact of a clinical examination/CBCT approach on the oral health status of patients hospitalized for IE and potentially to reduce IE new episodes.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying CBCT for people with infective endocarditis. The study is currently recruiting participants at 10 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTCBCT

Cone Beam Computed Tomography (CBCT) has a better sensitivity and sensibility to detect OIF.


Locations(10)

CHU Bordeaux - Site Pellegrin

Bordeaux, France

CHU Clermont-Ferrand

Clermont-Ferrand, France

CHU Grenoble

Grenoble, France

HCL

Lyon, France

APHM

Marseille, France

CHRU Nancy

Nancy, France

CHU Nantes

Nantes, France

AP-HP - Site Bretonneau

Paris, France

CHU Toulouse

Toulouse, France

CHRU Tours

Tours, France

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NCT06269679


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