RecruitingNCT06270095

" Fume Events in Air Flights: Consequences on Cabin Air Quality and on Aircrews Health of a French Fleet of Aircraft"

" Évènements Feux/Fumées/Odeurs Lors Des Vols aériens : conséquences Sur la qualité de l'Air à l'intérieur Des Cabines d'Avions et Sur la santé Des Personnels Navigants d'Une Flotte aérienne française " (AviSan)

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrollment

1,200 participants

Start Date

Apr 4, 2024

Study Type

OBSERVATIONAL

Conditions

Neurologic Disorder Neurologic Symptoms

Summary

The subject of the study focuses on commercial aircraft's cabins air quality, under conditions of both fume events and non-fume events. It also delves into the immediate and delayed repercussions of these events on the health of aviation crew members. The expological facet of this study is directed at the detection and quantification of organophosphorus compounds originating from engine oils. The epidemiological facet is geared towards the identification of potential neurological consequences.

Eligibility

Min Age: 18 YearsMax Age: 67 Years

Inclusion Criteria2

be of legal age (18 years)
have signed the consent form

Exclusion Criteria2

be pregnant
be over 67 years of age

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Interventions

DIAGNOSTIC_TESTNeurocognitive, neuromuscular and neurosensitive tests.

At T0, the subject realizes a neurocognive test and an self-assessment of health symptoms autonomously on its professional digital tablet. They also realizes two self questionnaires on their state of fatigue (Samn-Perelli Fatigue Scale) and anxiety (Hospital Anxiety and Depression scale). At T0 + 3 months, the subject follows a standardized medical examination carried out by a physician, assessing neuromuscular score using the Medical Research Council questionnaire and assessing neurosensitivity score using the Incat Sensory Sum Score. If necessary, the DN4 questionnaire for neuropathic pain is used. The same neurocognitive tests than T0, and Samn-Perelli Fatigue Scale and Hospital Anxiety and Depression scale are also repeated.