Using TMS to Understand Neural Processes of Social Motivation
Personalized Neuromodulation Targeting Dysregulated Motivational Responses Underlying Social Avoidance Behavior
Auburn University
40 participants
Sep 30, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to use transcranial magnetic stimulation (TMS) to better understand the neural circuits associated with social motivation. Participant includes four study visits each that range from 1.5 - 3.0 hours in duration over approximately a one month period. The first study visit involves answering survey questions, a clinical interview, and computer tasks. The second study visit involves a magnetic resonance imaging (MRI) scan, computer tasks, and a brief TMS protocol. The second and third study visits involve a full session of TMS followed by an MRI scan and computer tasks. Adults in the Auburn/Opelika area and surrounding areas who avoid social situations, experience symptoms of depression or social anxiety, and are between 25 years old and 50 years old are eligible to participate.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
TMS will be administered using a Cool B-65 coil to a personalized right dlPFC region.
Locations(1)
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NCT06274112