RecruitingNCT06274593

Study of OCT Peripapillary Angiography in Patients With Advanced Glaucoma

Sponsor

Nantes University Hospital

Enrollment

50 participants

Start Date

Apr 27, 2024

Study Type

OBSERVATIONAL

Conditions

Glaucoma

Summary

Glaucoma is a chronic disease of the optic nerve, characterized by progressive loss of nerve cells in the retina, leading to progressive loss of peripheral and central vision. There are in fact several types of glaucoma, which is the world's second leading cause of blindness after cataracts, and the leading cause of irreversible blindness. To date, to our knowledge, there is no work analyzing the progression of angiographic OCT in patients with glaucoma. The main aim of this study is to compare the 3-year progression rate of 3 examinations in advanced glaucoma patients: one functional (visual field) and two anatomical (OCTa and OCTrnfl).

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is using a specialized eye-imaging technique (OCT angiography) to examine blood vessel changes around the optic nerve in people with advanced glaucoma. The goal is to better understand how blood flow changes relate to vision loss in glaucoma. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with glaucoma and are followed at Nantes University Hospital - Your glaucoma has caused significant vision field loss (greater than 10 dB) **You may NOT be eligible if...** - You have diabetic retinopathy, a retinal vein or artery blockage, or other vascular eye disease - You have a non-glaucoma cause of optic nerve damage (e.g., stroke-related vision loss) - You have retinal diseases like retinitis pigmentosa or macular degeneration - You have had certain retinal laser treatments or procedures - You have active eye inflammation (uveitis) or a dense cataract that blocks imaging - You are pregnant or breastfeeding - You are unable to hold your gaze steady for eye testing Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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