RecruitingNCT06275230

Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD

Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in Chronic Obstructive Pulmonary Disease

Sponsor

China-Japan Friendship Hospital

Enrollment

30 participants

Start Date

Mar 20, 2024

Study Type

OBSERVATIONAL

Conditions

Chronic Obstructive Pulmonary Disease

Summary

The goal of this study is to proliferate human lung stem cell in vitro in order to establish a lung organoid derived from patients with COPD. The main question it aims to answer are: * Can human lung stem cell proliferate in vitro. * Can a lung organoid derived from patients with COPD be established. Participants will be sampled during pulmonary bronchoscope for organoid establishment.

Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This research study is collecting lung tissue samples during routine bronchoscopy from COPD patients in order to grow lung stem cells in the lab and build "mini-lung" models (organoids). These lab models help researchers study COPD and test new treatments without needing to repeatedly biopsy patients. **You may be eligible if...** - You are under 55 years old (any gender) - You have COPD and are already scheduled to have a bronchoscopy with biopsy - You do not have any genetic diseases or other respiratory conditions beyond COPD **You may NOT be eligible if...** - Your doctor determines you are not a good candidate due to difficulty obtaining samples, difficulty attending follow-up, or other serious medical conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

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NCT06275230

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