RecruitingNCT06277297

Prognotic Role of CMR in Takotsubo Syndrome

Exploring the eVolution in prognOstic capabiLity of mUlti-sequence Cardiac magneTIc resOnance in patieNts Affected by Takotsubo Cardiomyopathy


Sponsor

University of Cagliari

Enrollment

350 participants

Start Date

Nov 9, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The primary objective of this observational registry is to develop a comprehensive clinical and imaging score (incorporating echocardiography and cardiac magnetic resonance data) that enhances risk stratification for patients with Takotsubo syndrome. The secondary objectives of this registry are as follows: Investigate the diagnostic value of cardiac magnetic resonance parameters in predicting in-hospital and long-term outcomes in patients with Takotsubo syndrome. Compare the proposed risk stratification score for patients with Takotsubo syndrome with previously existing scores. Investigate the contribution of machine learning models in predicting in-hospital and long-term outcomes compared to standard clinical scores. The design and rationale of this registry are available at 10.1097/RTI.0000000000000709


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Takotsubo syndrome diagnosis (according to Position Statement of the European Society of Cardiology Heart Failure Association)
  • Adult patients ( \> 18y old)
  • Availability at baseline of clinical variables, standard transthoracic echocardiography, and cardiovascular magnetic resonance acquisition

Exclusion Criteria6

  • \<18 y old
  • Lack of transthoracic echocardiography and cardiovascular magnetic resonance examinations
  • Preexisting cardiomyopathies
  • Previous myocardial infarction
  • Suspected or known prior irreversible myocardial damage
  • Valvular heart disease

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Locations(1)

University of Cagliari

Cagliari, Italy, Italy

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NCT06277297


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