RecruitingNot ApplicableNCT06285708

Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD


Sponsor

Ohio State University

Enrollment

100 participants

Start Date

Feb 26, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD). Prolonged exposure (PE) and crisis response plan (CRP) have demonstrated empirical support for reducing suicide attempts as compared to treatment as usual. However, no studies to date have assessed their effectiveness when used in combination. In light of this knowledge gap, the primary objective of this study will be to test the effectiveness of PE augmented with CRP as compared to PE with care as usual (self-guided treatment plan), an active comparator, for the reduction of suicide ideations and attempts for individuals with comorbid PTSD.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether an enhanced version of Prolonged Exposure therapy — a proven treatment for PTSD — can be made more effective for people who are also experiencing suicidal thoughts. **You may be eligible if...** - You have a current diagnosis of PTSD or significant PTSD symptoms - You are able to speak and understand English - You are able to go through the informed consent process **You may NOT be eligible if...** - You have a substance use disorder that requires medical management - You are at immediate risk of suicide and need inpatient care or a crisis-focused treatment program - You have a mental health condition (such as active psychosis or mania) that would make it unsafe to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

BEHAVIORALProlonged exposure

PE therapy is a manualized cognitive behavioral therapy consisting of imaginal exposure (repeated recounting of the most disturbing traumatic memory) followed by processing thoughts and feelings related to the imaginal experience; in-vivo exposure (approaching trauma-related situations); psychoeducation about PTSD; and controlled breathing training. Between sessions, participants listen to audio recordings of the imaginal recounting daily and complete in-vivo exercises. Typically, PE is delivered weekly for 10-12, 90-minutes sessions. For this study, participants will complete daily 60-minute sessions for 10 consecutive weekdays during a 2-week period.


Locations(1)

The Ohio State University

Columbus, Ohio, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06285708


Related Trials