Effect of Acetazolamide on Diuresis and Natriuresis in Patients With Acute Heart Failure (SANDI STUDY)

This study is testing whether adding acetazolamide (a diuretic drug that works differently from standard water pills) helps patients hospitalized with acute heart failure remove excess fluid more effectively. **You may be eligible if...** - You were admitted to the hospital for acute heart failure with signs of fluid overload (swelling, fluid in the lungs, or fluid around the lungs) - Your heart failure blood marker (BNP or NTproBNP) is elevated at admission - You are already being treated with furosemide and an SGLT2 inhibitor but still have signs of congestion **You may NOT be eligible if...** - Your blood pressure is very low - You have taken acetazolamide in the past month - You have severely reduced kidney function or need dialysis - You have Type 1 diabetes - You are likely to need IV inotropes or other intensive heart medications during the study Talk to your doctor to see if this trial is right for you.