RecruitingPhase 1NCT06285890

Phase I Study of HC-7366 for Acute Myeloid Leukemia


Sponsor

M.D. Anderson Cancer Center

Enrollment

18 participants

Start Date

May 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To find a recommended dose of HC-7366 to patients with AML. The safety and effects of this drug combination will also be studied.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This early-phase study is testing the safety and appropriate dose of a new drug called HC-7366 in patients with acute myeloid leukemia (AML) — a type of blood cancer — whose disease has returned or did not respond to prior treatment. **You may be eligible if...** - You are 18 or older with a confirmed diagnosis of AML or a pre-leukemia condition with high blast counts - Your disease has come back or did not respond to prior treatment - There are no remaining standard treatment options available to you - Your liver and kidney function meet minimum health thresholds **You may NOT be eligible if...** - You have a specific subtype of AML called acute promyelocytic leukemia (APL) - You have not received appropriate prior therapies - You have serious organ problems or uncontrolled infections - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGHC-7366

Given by PO


Locations(1)

MD Anderson Cancer Center

Houston, Texas, United States

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NCT06285890


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