RecruitingNot ApplicableNCT06290544

Cardiovascular Risk Assessment in a Cohort of Italian Patients With Type 1 Diabetes Mellitus (CARDT1)

Cardiovascular Risk Assessment in a Cohort of Italian Patients With Type 1 Diabetes Mellitus - CARDT1

Sponsor

Centro Cardiologico Monzino

Enrollment

200 participants

Start Date

Nov 29, 2021

Study Type

INTERVENTIONAL

Conditions

Cardiovascular Diseases Diabetes Mellitus, Type 1

Summary

This is a multicenter prospective collection of data with diagnostic procedures different from standard clinical care in a specific cohort of patients, aimed to evaluate cardiovascular risk stratification with the European Society of Cardiology (ESC)/European Association for the Study of Diabetes (EASD) guidelines and "The Steno Type 1 Risk Engine" algorithm. The correlation between CVD risk, atherosclerosis, and microvascular complications of diabetes (retinopathy, nephropathy, and neuropathy) will then be evaluated, and the impact of glycemic variability and other glucose metrics on vascular damage will be characterized. The investigators plan to enroll at least 200 consecutive type 1 diabetes mellitus (T1DM) patients who meet all the inclusion criteria and none of exclusion criteria.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is tracking cardiovascular (heart and blood vessel) health in Italian patients with type 1 diabetes over time. The goal is to better understand the risks of heart disease in people with this condition so doctors can improve prevention and care. **You may be eligible if...** - You are 18 years or older - You have a confirmed diagnosis of type 1 diabetes - You are willing to sign an informed consent form **You may NOT be eligible if...** - You are under 18 years old - You are currently pregnant - You have type 2 diabetes or diabetes caused by another medical condition Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERStandard of care plus additional examinations

The patient will undergo good clinical practice examinations according to guidelines plus The patient will undergo to the evaluation of endothelial dysfunction with ENDOPAT 2000 and whole blood sampling for future omics studies