Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure
Clinical Effectiveness and Implementation of Trauma-Informed Guilt Reduction Therapy Compared to Prolonged Exposure (TrIGR)
Veterans Medical Research Foundation
158 participants
Dec 1, 2024
INTERVENTIONAL
Conditions
Summary
The goal of this clinical trial is to learn if receiving Trauma-Informed Guilt Reduction (TrIGR) Therapy is as effective as receiving Prolonged Exposure Therapy among veterans with PTSD and trauma related guilt. The main questions it aims to answer are: Will TrIGR be comparable to PE in terms of PTSD symptom reduction? Will it TrIGR be comparable to PE in improving functioning and reducing depression symptoms? Will it be superior in improving trauma-related guilt and shame?
Eligibility
Inclusion Criteria5
- U.S. Veterans age 18 or older who served in the military since the start of Operation Enduring Freedom/Operation Iraqi Freedom; OEF/OIF)
- meets diagnostic criteria for PTSD;
- a score of 2 or higher ("true" to "extremely true") on feeling trauma-related guilt much or all of the time or scoring 3 or higher ("very true" or "extremely true") on at least one guilt cognition factor (hindsight bias/responsibility, wrongdoing, or lack of justification) on the Trauma Related Guilt Inventory
- not currently receiving trauma-focused treatment such as PE or CPT
- willingness to attend psychotherapy and assessment sessions
Exclusion Criteria5
- current risk of suicidal/homicidal behavior that requires immediate intervention
- current severe substance use disorder (in the past two months) based on DSM-5 criteria
- current unmanaged psychosis or mania
- life threatening or unstable medical illness
- inability to read
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Behavioral therapy for trauma related guilt and shame
Behavioral exposure therapy for PTSD
Locations(3)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06296589