Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia

This study looks at whether a personalized physical activity program can improve the quality of life for people with chronic lymphocytic leukemia (CLL) who are just starting a medication called ibrutinib. Participants will wear a smartwatch, use a digital tool, and follow an exercise plan tailored to them. **You may be eligible if...** - You have CLL and are starting ibrutinib for the first time or for relapsed disease (treatment started within the last 8 days) - You are willing to follow a personalized physical activity program - You have a smartphone, laptop, or tablet and access to the internet at home - You are willing to wear a connected smartwatch 24 hours a day for the whole study **You may NOT be eligible if...** - You are pregnant or planning to become pregnant - You are unable to safely exercise - You have used an experimental drug within the past 90 days - You are already enrolled in another interventional clinical study - You would have difficulty using digital tools on your own Talk to your doctor to see if this trial is right for you.