RecruitingNot ApplicableNCT06302985

Atomized Inhalation ICG for Treatment of Congenital Lung Malformations

Application of Atomized Inhalation ICG in Thoracoscopic Surgery for Pulmonary Sequestration in Children: a Multicentre Prospective Study


Sponsor

Jiexiong Feng

Enrollment

50 participants

Start Date

Mar 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

To investigate the safety and effectiveness of preoperative aerosol inhalation ICG solution for thoracoscopic accurate resection of congenital lung malformations in children.


Eligibility

Min Age: 3 MonthsMax Age: 14 Years

Inclusion Criteria1

  • children with congenital lung malformations diagnosed by CT or MRI scan

Exclusion Criteria1

  • \. ages <3 months and >14 years 2. complicated other life-threatening disease; 3. complicated severely pulmonary infection

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Interventions

PROCEDUREatomized inhalation ICG before thoracoscope pneumonectomy

Preoperative preparation ICG solution dissolved in 5ml of normal saline (dose 0.5mg/kg) was inhaled 30 minutes before surgery. Operation method After entering the chest cavity, the fluorescence endoscope was switched to the fluorescence display mode, and the fluorescence-stained normal lung tissue and non-stained lesion tissue could be clearly displayed through the display screen, and the external boundary of the lesion was marked with an electric hook. The mediastinal pleura and pulmonary pleura were opened along the boundary of the lesion, and the lung tissue was split along the gap between the lesion and the lung tissue with an electric coagulation hook and an ultrasonic knife, and the lesion arteries and bronchi were freed.


Locations(1)

Tongji Hospital

Wuhan, Hubei, China

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NCT06302985


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