Children Clinical Trials

493 recruitingLast updated: June 18, 2026

There are 493 actively recruiting children clinical trials across 66 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, Toronto, Ontario, Canada, Lahore, Punjab Province, Pakistan. Updated daily from ClinicalTrials.gov.


Children Trials at a Glance

493 actively recruiting trials for children are listed on ClinicalTrialsFinder across 6 cities in 66 countries. The largest study group is Not Applicable with 236 trials, with the heaviest enrollment activity in Boston, Toronto, and Lahore. Lead sponsors running children studies include Riphah International University, Boston Children's Hospital, and Assistance Publique - Hôpitaux de Paris.

Treatments under study

About Children Clinical Trials

Looking for clinical trials for Children? There are currently 61 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Children trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Children clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 493 trials

Recruiting
Phase 3

A Study With Eptinezumab in Adolescents (12-17 Years) With Chronic Migraine

Chronic Migraine in Children
H. Lundbeck A/S285 enrolled84 locationsNCT04965675
Recruiting

Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses

Speech DisordersDentofacial DeformitiesSpeech Sound Disorder+7 more
University of North Carolina, Chapel Hill180 enrolled1 locationNCT04117360
Recruiting
Not Applicable

NEPTUNE Match Study

Nephrotic Syndrome in ChildrenAlport SyndromeFocal Segmental Glomerulosclerosis+6 more
University of Michigan375 enrolled16 locationsNCT04571658
Recruiting
Not Applicable

Effects of Cartoons and Mobile Games on Preoperative Anxiety and Fear in Children With Appendicitis: An RCT

Preoperative AnxietyFearChildren+1 more
Ankara City Hospital Bilkent69 enrolled1 locationNCT07640230
Recruiting
Phase 3

GB06 Phase III Trial for Pediatric Growth Hormone Deficiency

Growth Hormone Deficiency (GHD)Growth Hormone Deficiency in ChildrenGrowth Hormone Deficiency, Pediatric
Kexing Biopharm Co., Ltd.192 enrolled1 locationNCT07553351
Recruiting
Phase 4

Trial of an AI-enabled Digital Stethoscope to Improve Antibiotic Stewardship

Respiratory Infections in Children
Johns Hopkins University2,500 enrolled1 locationNCT07362433
Recruiting
Phase 3

Efficacy of Solifenacin, Mirabegron and Combination Therapy in Children With Daytime Urinary Incontinence (BeDry)

Urinary Incontinence in Children
University of Aarhus236 enrolled5 locationsNCT06551246
Recruiting

Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations

Healthy ChildrenChildren With Neurodevelopmental DisordersChildren With Neuropsychiatric Disorders+1 more
National Institute of Mental Health (NIMH)244 enrolled5 locationsNCT04639830
Recruiting
Not Applicable

Supraspinal Processing of Sensory Aspects of Pain

Musculoskeletal PainFibromyalgiaFunctional Abdominal Pain Syndrome+2 more
Children's Hospital Medical Center, Cincinnati255 enrolled1 locationNCT05814497
Recruiting
Phase 2

Phase II Study of Chidamide-Dinutuximab Beta-Irinotecan-Temozolomide for Refractory/Relapsed Neuroblastoma in Children

Neuroblastoma (NB)Neuroblastoma in Children
Tianjin Medical University Cancer Institute and Hospital27 enrolled1 locationNCT07318831
Recruiting
Phase 3

A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

Chronic Kidney DiseaseProteinuriaChildren
Bayer100 enrolled179 locationsNCT05457283
Recruiting
Not Applicable

The Effects of Sodium Fluoride and Chlorhexidine Use on Salivary IL-6 and Matrix Metalloproteinase Levels in Children With Active Caries

Dental CariesDental Caries in Children
Gül Keskin80 enrolled1 locationNCT07609797
Recruiting
Phase 1

Tegavivint With Gemcitabine in Patients With Relapsed or Refractory Osteosarcoma

Refractory OsteosarcomaOsteosarcoma in ChildrenOsteosarcoma Recurrent+1 more
Emory University24 enrolled1 locationNCT07144254
Recruiting
Not Applicable

Repetitive Transcranial Magnetic Stimulation Combined With Language Training for Language Disorders in Children With Global Developmental Delay

Global developmental delayRepetitive Transcranial Magnetic Stimulation (rTMS)Developmental Delay Disorder+1 more
Xiangya Hospital of Central South University50 enrolled1 locationNCT07369960
Recruiting
Phase 1Phase 2

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled30 locationsNCT06783309
Recruiting

Calcium Isotope Ratios to Assess Calcium Bone Balance in Dialysis Children Receiving Cinacalcet

Children Over 3 Undergoing Dialysis With Secondary Hyperparathyroidism
Hospices Civils de Lyon20 enrolled7 locationsNCT07007338
Recruiting
Phase 3

Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in Ambulatory Participants With Duchenne Muscular Dystrophy (FORZETTO)

Muscular Dystrophy, DuchenneDMDNeuromuscular Diseases (NMD)+10 more
Dyne Therapeutics90 enrolled1 locationNCT07608432
Recruiting

Thai Version of the Pediatric Quality of Recovery Score (PedSQoR): Translation and Psychometric Validation Study

Postoperative Recovery in Children
Mahidol University130 enrolled1 locationNCT07378501
Recruiting
Not Applicable

Pathway to Peanut Tolerance

Food Allergy in ChildrenFood Allergy Peanut
Chinese University of Hong Kong125 enrolled1 locationNCT07592780
Recruiting
Phase 4

Assessment of Safety of the Use of Fenfluramine in Children With Dravet Syndrome Under 24 Months of Age

Dravet Syndrome (DS)Children Under 2 Years
University of Colorado, Denver5 enrolled1 locationNCT06598449