Children Clinical Trials

506 recruitingLast updated: July 17, 2026

There are 506 actively recruiting children clinical trials across 66 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include Boston, Massachusetts, United States, Toronto, Ontario, Canada, Lahore, Punjab Province, Pakistan. Updated daily from ClinicalTrials.gov.


Children Trials at a Glance

506 actively recruiting trials for children are listed on ClinicalTrialsFinder across 6 cities in 66 countries. The largest study group is Not Applicable with 241 trials, with the heaviest enrollment activity in Boston, Toronto, and Lahore. Lead sponsors running children studies include Riphah International University, Boston Children's Hospital, and Assistance Publique - Hôpitaux de Paris.

Treatments under study

About Children Clinical Trials

Looking for clinical trials for Children? There are currently 64 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Children trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Children clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 506 trials

Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Heart FailurePainInsomnia+22 more
Duke University5,000 enrolled51 locationsNCT04278404
Recruiting

Prospective Multicentre Study on Symptoms in First-onset Bronchial Asthma in Children and Adolescents

AsthmaDyspneaPneumonia+8 more
Charles University, Czech Republic80 enrolled1 locationNCT06201494
Recruiting
Phase 1Phase 2

Optimizing Hydroxyurea Therapy in Children With Sickle Cell Anemia In Malaria Endemic Areas: The NOHARM Maximum Tolerated Dose (MTD) Study

Sickle Cell DiseaseSickle Cell Anemia in Children
Children's Hospital Medical Center, Cincinnati250 enrolled1 locationNCT07708714
Recruiting

Y of Central Maryland Head Start Asthma Implementation

ImplementationAsthma in ChildrenPreschool Children
Johns Hopkins University500 enrolled2 locationsNCT05004714
Recruiting

Cerebral Palsy and the Study of Brain Activity During Motor Tasks

Cerebral PalsyChildren
National Institutes of Health Clinical Center (CC)320 enrolled1 locationNCT01829724
Recruiting
Not Applicable

The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care

Appendicitis AcuteAcute Abdomen in Children
University Medical Center Groningen566 enrolled1 locationNCT06762275
Recruiting
Not Applicable

Gamification Effects on the 6-Minute Walk Test in Children

Neuromuscular Diseases in Children
David Toupin20 enrolled1 locationNCT07216339
Recruiting

Pediatric Movement Disorders of Unknown Etiology in Vietnam (VPeMD)

Movement Disorders in ChildrenNeurogenetic DisordersNeuro Developmental Delay
University of Medicine and Pharmacy at Ho Chi Minh City50 enrolled2 locationsNCT07695610
Recruiting
Not Applicable

Let's E.A.T.! (Eating With Assistive Technology): An Intervention to Support Children With Feeding Tubes and Tracheostomies

Children with medical complexityTracheostomyFeeding Tube+1 more
University of Chicago40 enrolled1 locationNCT06525818
Recruiting
Not Applicable

Melatonin Adolescent Research Study

Sleep Disorders in Children
Loma Linda University80 enrolled2 locationsNCT04588233
Recruiting
Phase 4

Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency

Cholestatic Liver DiseaseChildrenVitamin D Deficiency+1 more
Chulalongkorn University54 enrolled1 locationNCT07670611
Recruiting
Phase 4

Prevention With Ismigen of RTIs in Kids

Healthy ChildrenRespiratory Tract Infections (RTI)
Lallemand Pharma AG224 enrolled10 locationsNCT07578012
Recruiting
Not Applicable

Implementing Powered Mobility in Early Childhood Settings for Children With Cerebral Palsy

Developmental DisabilityRehabilitationCerebral Palsy Children+3 more
Oregon Health and Science University70 enrolled3 locationsNCT07220590
Recruiting

CIMR Neuromuscular Research Biobank

Neuromuscular DiseasesNeuromuscular Diseases in ChildrenNeuromuscular Disorder
Virginia Commonwealth University500 enrolled1 locationNCT05434572
Recruiting

MiniMed Fit Payload Wear Pediatric Study

Diabetes (Insulin-requiring, Type 1 or Type 2)Diabetes (DM)Diabetes in Adolescence+1 more
Medtronic MiniMed, Inc.100 enrolled3 locationsNCT07675161
Recruiting
Phase 2Phase 3

Oral Versus Intravenous Magnesium on Emergence Delirium

Emergence DeliriumChildrenMagnesium+1 more
Tanta University360 enrolled1 locationNCT07655817
Recruiting
Not Applicable

Differences in Rest, Emotion, and Arousal Modulation in Youth

SleepAutismSleep Disturbances in Children
University of Pittsburgh60 enrolled1 locationNCT07476937
Recruiting
Phase 1Phase 2

CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)

Type 1 DiabetesType 1 Diabetes MellitusType 1 Diabetes Mellitis+7 more
COUR Pharmaceutical Development Company, Inc.72 enrolled33 locationsNCT06783309
Recruiting

19F MRI in Healthy Children and Children With Mild Cystic Fibrosis Lung Disease

Cystic Fibrosis in Children
University of North Carolina, Chapel Hill15 enrolled1 locationNCT06066723
Recruiting
Not Applicable

SMART@Home Feasibility Trial

AsthmaAsthma in Children
Children's Hospital Medical Center, Cincinnati25 enrolled1 locationNCT06159127