Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis
Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis - Toxoplasmosis in ICU (TOXIC)
Assistance Publique - Hôpitaux de Paris
200 participants
Aug 1, 2024
OBSERVATIONAL
Conditions
Summary
Toxoplasmosis is a common infection whose clinical severity can sometimes justify admission to intensive care, especially in immunocompromised patients. This study should make it possible to evaluate the impact of different anti-infective treatment regimens and to highlight clinical-biological and prognostic differences depending on the type of underlying immunosuppression.
Eligibility
Inclusion Criteria3
- Adult patient hospitalized in intensive care
- At least 1 organ failure (SOFA> or =2)
- PCR toxoplasmosis on CSF, blood, BAL, or bone marrow positive within 7 days before or after admission to ICU
Exclusion Criteria3
- Post-mortem diagnosis
- Primary outcome not available
- Patient living informed and not opposed to the reuse of their data in this research.
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06305468