RecruitingNot ApplicableNCT06309238

Intensive Weight Loss Intervention Versus Bariatric Surgery for Adults With Severe and Complex Obesity: the LightBAR Randomised Trial

Intensive Weight Loss Intervention Versus Bariatric Surgery for Adults With Severe and Complex Obesity: the LightBAR Randomised Trial. Lighthouse Consortium on Obesity Management (LightCOM) Trial no 4

Sponsor

Carsten Dirksen

Enrollment

500 participants

Start Date

May 8, 2024

Study Type

INTERVENTIONAL

Conditions

Obesity

Summary

With this trial, the aim is to assess the benefits and harms of a non-surgical intensive weight loss intervention that includes total dietary replacements, behavioural support and weight-loss medication compared with bariatric surgery for people with severe and complex obesity. The interpretation of the results will help inform future care pathways for people with obesity in whom bariatric surgery is currently the only available effective treatment option.

Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Bariatric surgery and a behavioral approach called Intensive weight loss intervention for people with obesity. The study is currently recruiting participants at 10 locations. People eligible for this study include aged 18 Years to 60 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALIntensive weight loss intervention

Intensive weight loss intervention, incl. total meal replacements, behavioural support, and weight loss medication

PROCEDUREBariatric surgery

Roux-en-Y Gastric Bypass (RYGB) or Sleeve Gastrectomy (SG)

Locations(10)

Steno Diabetes Center Aarhus, Aarhus Universitets Hospital

Aarhus, Denmark

The Department of Medicine and Department of Surgery, University Hospital of South West Jutland

Esbjerg, Denmark

The Department of Medicine and the Gastro Unit, Copenhagen University Hospital - Amager and Hvidovre

Hvidovre, Denmark

Department of Surgery, Viborg Regional Hospital

Viborg, Denmark

St Richard's Hospital

Chichester, Sussex, United Kingdom

Hartlands Hospital, University Hospitals Birmingham NHS Foundation Trust

Birmingham, United Kingdom

Southmead Hospital, North Bristol NHS Trust

Bristol, United Kingdom

The Whittington Hospital

London, United Kingdom

Sunderland Royal Hospital

Sunderland, United Kingdom

Musgrove Park Hospital, Somerset Foundation NHS Trust

Taunton, United Kingdom

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NCT06309238

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