RecruitingNCT06311617

Retinal Vascular Changes During Pregnancy

Understanding Retinal Vascular Changes During Pregnancy and the Impact on Maternal and Fetal Health


Sponsor

Vanderbilt University Medical Center

Enrollment

90 participants

Start Date

Feb 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to better understand how the back part of the eye-called the retina and the choroid-changes during pregnancy. Specialized photos of the eye will be taken at three different timepoints: early in pregnancy (first or second trimester), late in pregnancy (third trimester), and after delivery. This imaging is non-invasive and does not require contact with the surface of the eye. The photos taken will allow assessment of specific parameters, like blood flow and the health of specialized cells that support vision. Understanding how the eyes change during pregnancy may help guide how retina specialists understanding of retinal disease during pregnancy and better inform pregnancy outcomes.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria3

  • Patient age 18 years and older
  • Patient able to provide informed consent
  • Pregnant at time of enrollment and in the 1st or 2nd trimester of pregnancy

Exclusion Criteria2

  • Other ocular disease that prevents imaging (significant cataract or other media opacity)
  • Unable to comply with imaging or follow-up through duration of study

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Interventions

DIAGNOSTIC_TESTOptical coherence tomography

Non-mydriatic fundus photography and optical coherence tomography will be performed at 3 timepoints


Locations(1)

Vanderbilt University Medical Center

Nashville, Tennessee, United States

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NCT06311617


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