RecruitingNCT06313944

German Registry of Alzheimer's Disease Treated With Transcranial Pulse Stimulation

German (GE) Multicenter Prospective Data Collection (Registry) on Treatment With Transcranial Pulse Wave Stimulation (TPS) in Patients With Alzheimer's Disease (A)


Sponsor

Heinrich-Heine University, Duesseldorf

Enrollment

100 participants

Start Date

Aug 6, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

This study will primarily investigate the safety and secondarily the effect and applicability of Transcranial Pulse Wave Stimulation (TPS) for the treatment of Alzheimer's disease in the context of a PMCF study (Post-Market Clinical Follow-up). The multicenter, prospective data collection should help to optimize the stimulation protocol, as well as to record frequent to occasional adverse effects of the product and cognitive, affective and subjective scores.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This is a German registry study tracking real-world outcomes for Alzheimer's disease patients who receive transcranial pulse stimulation (TPS) — a non-invasive brain stimulation technique that uses ultrasound pulses directed at the brain to try to improve cognition and slow decline. **You may be eligible if...** - You are between 18 and 85 years old - You have a clinical diagnosis of Alzheimer's syndrome, marked by gradual worsening of memory and daily functioning for more than 6 months - You are receiving TPS treatment at a specialized neurology or psychiatry center - Brain imaging and biomarker tests (CSF or PET scan) supporting Alzheimer's disease are helpful but not required **You may NOT be eligible if...** - You do not have a clinical diagnosis consistent with Alzheimer's disease or the Alzheimer's continuum - You are not receiving TPS treatment at a participating center - You are outside the age range of 18–85 years Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTRegistry

Clinical data collection of patients scheduled for on-label treatment


Locations(6)

Ernst von Bergmann Klinikum - Klinik für Neurologie und Klinische Neuropsychologie

Potsdam, Brandenburg, Germany

Evangelische Krankenhausstiftung Oldenburg - Universitätsklinik für Neurologie

Oldenburg, Lower Saxony, Germany

Universitätsklinikum Bonn - Klinik für Parkinson, Schlaf- und Bewegungsstörungen

Bonn, North Rhine-Westphalia, Germany

Neurologische Praxis Prof. Wojtecki

Neuss, North Rhine-Westphalia, Germany

Hospital zum Heiligen Geist GmbH & Co KG Klinik für Neurologie und Neurorehabilitation

Kempen, Germany

Praxis Dr. Schwarz

Ulm, Germany

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06313944


Related Trials