RecruitingNot ApplicableNCT06319014

Physical Activity to Mitigate PreEclampsia Risk

Physical Activity to Mitigate PreEclampsia Risk (PAMPER)

Sponsor

East Carolina University

Enrollment

224 participants

Start Date

Jun 24, 2024

Study Type

INTERVENTIONAL

Conditions

Pre-Eclampsia

Summary

The purpose of this study is to compare the effects of aerobic (AE), resistance (RE), and combination (AERE) exercise throughout pregnancy on selected maternal and fetal/neonatal physiological variables in women at-risk for preeclampsia. The central hypothesis of this project is that exercise will decrease severity and occurrence of preeclampsia symptoms, thus improving maternal, pregnancy, and birth outcomes. Aim 1. Determine the influence of different exercise modes during pregnancy at risk of preeclampsia on maternal cardiometabolic health. Aim 2. Determine the most effective exercise mode in pregnancy at risk of preeclampsia on improving birth and infant health outcomes.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study looks at whether a structured physical activity program during early pregnancy can lower the risk of preeclampsia — a dangerous condition in pregnancy characterized by high blood pressure. Sedentary pregnant women are enrolled and assigned to either an exercise program or a control group. **You may be eligible if...** - You are a woman between 18 and 40 years old - You are pregnant and less than 16 weeks along - You are carrying a single baby - Your BMI is between 18.5 and 45 - You are currently sedentary (not regularly exercising) - Your obstetric provider has cleared you to exercise **You may NOT be eligible if...** - You have a pre-existing chronic condition such as HIV or lupus - You are taking medications that could affect fetal development - You do not have a phone or email for follow-up contact Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.