Multi-Omics for Maternal Health After Preeclampsia

This study collects biological samples and health data from pregnant women during and after pregnancy to understand why some women develop preeclampsia (dangerously high blood pressure during pregnancy) and how it affects long-term heart health, using advanced multi-omics analysis (studying genes, proteins, and other biological data together). **You may be eligible if...** - You are 18 to 50 years old - You are 10 to 24 weeks pregnant at enrollment - You are carrying a single baby - You plan to deliver at UC San Diego or Vanderbilt University Medical Center **You may NOT be eligible if...** - You are unable to give informed consent - Your baby has a known chromosomal or structural abnormality, or the pregnancy has ended - You have a history of cancer requiring major surgery or chemotherapy - You are carrying multiples (twins, triplets, etc.) - You have a known chromosomal abnormality (mother or baby) - You plan to keep your placenta after delivery - You are institutionalized for a psychiatric condition or incarcerated Talk to your doctor to see if this trial is right for you.