RecruitingNot ApplicableNCT06322888

Resistance and Aerobic Exercise for Prevention in Women With Dense Breasts (REP-D)


Sponsor

Dana-Farber Cancer Institute

Enrollment

46 participants

Start Date

Mar 28, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to learn more about how exercise might lower the risk of developing breast cancer in women with dense breast tissue by studying changes that occur in breast tissue and blood as a result of participating in an exercise program. The names of the study groups in this study are: * Exercise Training Group * Waitlist Control Group


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 59 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether resistance and aerobic exercise can reduce breast density in women with dense breast tissue. Dense breasts are a risk factor for breast cancer, and researchers want to find out if exercise can lower that risk by reducing breast density over time. **You may be eligible if:** - You are a woman between 18 and 59 years old - Your most recent mammogram showed heterogeneously dense or extremely dense breast tissue (BIRADS category 3 or 4) - You currently exercise less than 60 minutes per week at moderate or vigorous intensity - You are not pregnant or breastfeeding - You can read and speak English **You may NOT be eligible if:** - You are unable to walk two blocks at any pace - You have a history of breast cancer - You have physical limitations that prevent exercise participation - You are pregnant or currently breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALExercise Training Program

A 12-week aerobic and resistance-training exercise intervention with a certified exercise trainer in person or virtually. FitBit activity tracker, resistance bands, hand weights, and stationary bike will be provided to participants. Hand weights will be returned at end of study.


Locations(2)

Brigham and Women's Hospital

Boston, Massachusetts, United States

Dana Farber Cancer Institute

Boston, Massachusetts, United States

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NCT06322888


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