RecruitingNCT06324149

Age-related Conditions in the Context of Multimorbidity and Frailty: Relative Weight of Frailty in Determining the Course and Outcomes of Different Chronic Diseases and Viceversa


Sponsor

IRCCS San Raffaele

Enrollment

500 participants

Start Date

Mar 7, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Observational study. Participants of the FRASNET study (9th March 2017, Protocol No. 24/INT/2017) who were evaluated in 2016 and 2017 will be contacted to be re-evaluated with multidimensional visits as part of the present study in order to assess trajectories and biomarkers of frailty and sarcopenia. Moreover, are going to evaluate with the same multidimensional visits patients with mild cognitive impairment and dementia followed up at the Neurologic Unit of the San Raffaele Hospital.


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria3

  • Having participated in the FRASNET study or being a patient with mild cognitive impairment or dementia followed up at the Neurologic Unit of the San Raffaele Hospital
  • Ability to sign written informed consent
  • > 18 years old

Exclusion Criteria3

  • Life expectancy < 6 months
  • Unwillingness to participate in the study
  • Unstable clinical disease(for ex. serious acute pathologies)

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Interventions

DIAGNOSTIC_TESTcompletion of scales and questionnaires; venous blood sampling; muscle ultrasound; cardiac ultrasound; electrocardiogram; bioelectrical impedance analysis

The sub-investigator performs a multidimentional geriatric evaluation


Locations(1)

San Raffaele Hospital

Milan, Italy

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NCT06324149


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