RecruitingNot ApplicableNCT06325774

Radical Hypofractionated Radiotherapy for Localized Prostate Cancer

Safety and Efficacy Study of Hypofractionated Radiotherapy for Localized Prostate Cancer: a Single-arm Clinical Trial


Sponsor

Changhai Hospital

Enrollment

20 participants

Start Date

Sep 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this trial is to study the safety outcomes of hypofractionated radiotherapy in treating patients with localized prostate cancer. Hypofractionated radiotherapy delivers higher doses of radiotherapy in a shorter time period, may enabling the killing of more tumor cells with fewer side effects. Accumulating evidence has proven the safety and feasibility of hypofractionated radiotherapy for localized prostate cancer.But for localized prostate cancer,the optimal dose per fraction of hypofractionated radiotherapy is still on its way.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests a radiation therapy approach for prostate cancer called hypofractionated radiotherapy — where a higher dose is given over fewer sessions compared to traditional radiation. This can be more convenient for patients and may be equally effective. Researchers are evaluating its safety, effectiveness, and impact on quality of life. **You may be eligible if...** - You are 18 or older - You have been diagnosed with prostate cancer confirmed by biopsy - Your cancer is any stage that hasn't spread to distant organs (cTanyN0M0) - You are expected to live more than 5 years - You are in good general health (ECOG score 2 or less) - You are willing to participate after being informed of other treatment options **You may NOT be eligible if...** - You have already received treatment for prostate cancer (radiation, chemotherapy, hormone therapy, focal therapy) - You have had previous radiation to the pelvis or abdomen - You have another active cancer - You have severe urinary problems after surgery Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONHypofractionated radiation therapy

54 Gy in 15 daily fractions of 3.6 Gy to the prostate bed in the absence of disease progression or unacceptable toxicity.


Locations(1)

Changhai hospital

Shanghai, Shanghai Municipality, China

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NCT06325774


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