Localized Prostate Cancer Clinical Trials

12 recruiting

Localized Prostate Cancer Trials at a Glance

13 actively recruiting trials for localized prostate cancer are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in Shanghai, Taipei, and Toronto. Lead sponsors running localized prostate cancer studies include Changhai Hospital, David Oh, and Affidea Nu-med Center of Oncological DIagnostics and Therapy.

Browse localized prostate cancer trials by phase

Treatments under study

About Localized Prostate Cancer Clinical Trials

Looking for clinical trials for Localized Prostate Cancer? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Localized Prostate Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Localized Prostate Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Not Applicable

WATER IV Prostate Cancer

Localized Prostate Cancer
PROCEPT BioRobotics280 enrolled37 locationsNCT06651632
Recruiting
Phase 2

18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy

Localized Prostate Cancer
National Cancer Institute (NCI)130 enrolled1 locationNCT05155046
Recruiting
Phase 2Phase 3

PRO-BOOST-LC: Whole-Gland Boost Strategies Versus SBRT Monotherapy in PSMA-Staged Localized and Locally Advanced Prostate Cancer

Prostate Cancer (Adenocarcinoma)Stereotactic Body Radiation Therapy (SBRT)Localized Prostate Cancer+2 more
Affidea Nu-med Center of Oncological DIagnostics and Therapy1,200 enrolled1 locationNCT07426055
Recruiting
Not Applicable

Oxybutynin ER to Promote Early Continence Recovery After Robotic Prostatectomy: A Randomized Controlled Trial

Localized Prostate CancerPostoperative Urinary Incontinence
National Taiwan University Hospital135 enrolled1 locationNCT06966778
Recruiting
Early Phase 1

HCQ in Resectable Localized Prostate Cancer

Resectable Localized Prostate Cancer
Lionel.D.Lewis, MD20 enrolled1 locationNCT06408298
Recruiting
Phase 3

Is Adaptive SBRT for Prostate vs Image-guided Radiotherapy a True Evolution (ASPIRE)

Stereotactic Body RadiotherapyLocalized Prostate Cancer
University Health Network, Toronto320 enrolled1 locationNCT06825091
Recruiting
Not Applicable

The PRECISION Study: 3 Fractions of Prostate SBRT and RayPilot HypoCath Image Guidance

Localized Prostate Cancer
NHS Lothian100 enrolled1 locationNCT06117059
Recruiting
Phase 2

Neoadjuvant Atezolizumab-Based Combination Therapy in Men With Localized Prostate Cancer Prior to Radical Prostatectomy

Prostate CancerProstate AdenocarcinomaLocalized Prostate Cancer
David Oh68 enrolled2 locationsNCT03821246
Recruiting
Not Applicable

Radical Hypofractionated Radiotherapy for Localized Prostate Cancer

Localized Prostate Cancer
Changhai Hospital20 enrolled1 locationNCT06325774
Recruiting
Not Applicable

Hypofractionated Post-prostatectomy Radiotherapy (HYPORT)for Localized Prostate Cancer

Localized Prostate Cancer
Changhai Hospital428 enrolled1 locationNCT06325995
Recruiting

Clinical Study of HIFU for Localized Prostate Cancer

Localized Prostate Cancer
RenJi Hospital60 enrolled1 locationNCT06362577
Recruiting
Phase 2

Functional Image-Guided Carbon Ion Irradiation With Simultaneous Integrated Boost for Prostate Cancer

Localized Prostate Cancer
Shanghai Proton and Heavy Ion Center140 enrolled1 locationNCT05010343
Recruiting
Phase 3

Evaluation of Multiparametric Magnetic Resonance Imaging and Positron Emission Tomography with a [68Ga]gallium-labelled prostate-specific membrane antigen (PSMA) ligand for the Detection of Multiple Cancer Foci in Localized Prostate Cancer Patients – A Pilot Study

Localized Prostate Cancer
Queensland University of Technology20 enrolled1 locationACTRN12614000783628