RecruitingNot ApplicableNCT06334172
The Role of Oxytocin in Regulating Blood Glucose
Sponsor
University Hospital, Gentofte, Copenhagen
Enrollment
20 participants
Start Date
Jan 1, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
Investigating the effect of oxytocin on pancreatic endocrine functions by determining insulin and glucagon secretion within physiological ranges of plasma glucose.
Eligibility
Sex: MALEMin Age: 20 YearsMax Age: 50 Years
Inclusion Criteria1
- BMI 19-25 kg/m2
Exclusion Criteria11
- Diabetes
- Heart-, liver or kidney disease
- More than 14 units of alcohol weekly, or drug abuse
- Smoking or any kind of nicotine products
- Alanin aminotransferase (ALAT) ≥ 2 × normal range
- Estimated glomerular filtration rate (eGFR) < 60 ml/min/1,73m2 or creatinine above normal range
- Blood pressure > 140/90
- Hemoglobin < normal range
- Corrected QT Interval (Qtc) >0,45 sec. at electrocardiogram (ECG) at screening
- Known disease in the pituitary gland or previous pituitary surgery
- Any other disease/condition which the trial managers believe may affect participation in the trial
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Interventions
DRUGOxytocin
Oxytocin
OTHERPlacebo
Saline
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06334172
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