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RecruitingNCT04201600

Glucose Variability and Cognition in Prediabetes

Relations of Glucose Variability with Cognitive Function and Functional Status Among Older Adults At Risk for Diabetes

Sponsor

University of Maryland, Baltimore

Enrollment

30 participants

Start Date

Mar 1, 2022

Study Type

OBSERVATIONAL

Conditions

DepressionCognitive DeclinePrediabetesAgingGlucose Metabolism Disorders (Including Diabetes Mellitus)Functional Status

Summary

This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.

Eligibility

Min Age: 50 Years

Inclusion Criteria2

  • Aged 50 years and older
  • At least 8th grade education

Exclusion Criteria8

  • Diagnosed type 1 or type 2 diabetes
  • Current use of mediation for diabetes (oral hypoglycemic agents, insulin), or with diabetic properties (e.g., steroids)
  • Chronic disorders (cardiovascular disease, peripheral vascular disease, stroke, transient ischemic attack, chronic kidney disease, past year cancer)
  • Neurological disorders (e.g., Parkinson's, epilepsy, multiple sclerosis)
  • History of dementia or suspected dementia
  • Known HIV
  • Serious mental illness, psychosis, or use of psychotropic medication
  • Heavy alcohol use

Interventions

DEVICEContinuous Glucose Monitoring System (CGMS)

Continuous Glucose Monitoring System (CGMS)- minimally invasive sensors that measure glucose concentrations at 5-min intervals over several days.

Locations(1)

Baltimore VA Geriatric Research Education and Clinical Center (GRECC)

Baltimore, Maryland, United States

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NCT04201600

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