RecruitingNCT06334354

A Study of Changes in Thinking Related to Aging and Cancer in Breast Cancer Survivors (TRAC)

Cognitive Aging in Older Long-term Breast Cancer Survivors


Sponsor

Memorial Sloan Kettering Cancer Center

Enrollment

420 participants

Start Date

May 10, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to look at how differences in cognitive (mental) function develop over time in breast cancer survivors compared to volunteers without a history of cancer (healthy volunteers). Both cancer survivors and healthy volunteers (who are the same age as the cancer survivors) will participate in this study so the researchers can compare the results of neurocognitive testing (which looks at memory, attention, and information processing) on each group of participants.


Eligibility

Sex: FEMALEMin Age: 60 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how aging and breast cancer treatment affect thinking and memory over time in older women. Researchers are comparing breast cancer survivors with women who have never had breast cancer to better understand what causes cognitive changes in this age group. **You may be eligible if...** - You identify as female and are between 60 and 80 years old - You have access to a computer and internet - You score within a normal range on a brief memory/thinking test - You speak English fluently - If you take psychiatric medications (such as antidepressants), your dose has been stable for at least 2 months - Breast cancer survivors: you have a history of stage 0–3 breast cancer and have completed primary treatment **You may NOT be eligible if...** - You score in the impaired range on cognitive screening tests - You have a history of neurological conditions affecting cognition - You are currently undergoing active cancer treatment (other than maintenance therapy) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERAssessments

Sociodemographics, Deficit Accumulation Questionnaires, Remote Cognitive Assessment, Deficit Accumulation Questionnaires,Remote Cognitive Assessment

OTHERAssessment (Survivors Only)

\*Tumor/Treatment Variables (Survivors Only)

OTHERAPOE and DNA Isolation

Biospecimens procurement and processing


Locations(7)

Memorial Sloan Kettering Basking Ridge (All Protocol Activities)

Basking Ridge, New Jersey, United States

Memorial Sloan Kettering Monmouth (All protocol activities)

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen (All Protocol Activities)

Montvale, New Jersey, United States

Memorial Sloan Kettering Suffolk - Commack (All Protocol Activities)

Commack, New York, United States

Memorial Sloan Kettering Westchester (All Protocol Activities)

Harrison, New York, United States

Memorial Sloan Kettering Cancer Center

New York, New York, United States

Memorial Sloan Kettering Nassau (All Protocol Activities)

Uniondale, New York, United States

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NCT06334354


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