RecruitingNot ApplicableNCT06335667

mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer

Outcomes With Multi Parametric MRI (mpMRI) Compared to Diagnostic Transurethral Resection of Bladder Tumor (TURBT) in Patients With Suspected Muscle-Invasive Bladder Cancer - a Pilot Study


Sponsor

University of California, Irvine

Enrollment

30 participants

Start Date

Mar 27, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a pilot, single arm, prospective study that aims to validate the accuracy of the VI-RADS score obtained via multi-parametric magnetic resonance imaging (mpMRI) compared to pathologic cancer stage obtained via diagnostic transurethral bladder tumor resection (TURBT) as well as compare the clinical and quality of life outcomes between these diagnostic modalities in patients with suspected muscle-invasive bladder cancer (MIBC).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two approaches to diagnose muscle-invasive bladder cancer: an advanced MRI scan (mpMRI) versus the traditional surgical procedure (diagnostic TURBT, where a small scope removes tumor tissue for testing). The goal is to determine if MRI can accurately stage the cancer without requiring surgery first. **You may be eligible if...** - You are 18 years or older - Your doctor suspects you have muscle-invasive bladder cancer based on an initial cystoscopy (bladder inspection) - You have a good enough functional status (ECOG 0–3) - You are willing and able to follow the study schedule **You may NOT be eligible if...** - You had a TURBT or any bladder cancer treatment within the past 120 days - You are unable to tolerate an MRI (e.g., have a pacemaker, metal implants, or severe claustrophobia) - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTmpMRI + Diagnostic TURBT

mpMRI in addition to the TURBT surgical procedure


Locations(1)

Chao Family Comprehensive Cancer Center University of California, Irvine

Orange, California, United States

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NCT06335667


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