RecruitingNCT06336174

Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Artery Stenosis Patients: A Cohort Study

Cognitive Decline and Underlying Mechanisms in Symptomatic Intracranial Atherosclerotic Stenosis Patients: A Multicenter Cohort Study


Sponsor

Anhui Medical University

Enrollment

100 participants

Start Date

Nov 1, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to explore the mechanism of cognitive impairment in patients with symptomatic intracranial atherosclerotic stenosis (ICAS), and further plans to explore the impact of different treatment options on cognitive function in symptomatic ICAS patients.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin and a procedure called Endovascular therapy,Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin for people with cerebrovascular event, cognitive impairment, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin

All patients received standard medical management, including dual antiplatelet therapy (aspirin and clopidogrel) for three months with aspirin or clopidogrel monotherapy thereafter and high-dose statin, and treatment of hypertension to guideline targets.

PROCEDUREEndovascular therapy,Aspirin Tablet, Clopidogrel Bisulfate Tablets and Atorvastatin

All patients underwent endovascular therapy and received standard medical management after surgery, including dual antiplatelet therapy (aspirin and clopidogrel) for three months with aspirin or clopidogrel monotherapy thereafter and high-dose statin, and treatment of hypertension to guideline targets.


Locations(1)

Anhui Medical University

Hefei, Anhui, China

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NCT06336174


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