A Validation Study to Determine Concordance of Liquid Biopsy and Breast Cancer Diagnosis

This study is validating a blood test (liquid biopsy) that looks for traces of breast cancer DNA in the bloodstream, comparing it against standard mammography to see how well it detects breast cancer at various stages — including in women who have had abnormal or normal mammograms. **You may be eligible if...** - You are a woman aged 18 or older - You are scheduled for a routine screening mammogram or have already had one in the past 6 months, with no personal history of breast cancer (Screening Mammography Cohort), OR - You recently had an abnormal mammogram or MRI result (BIRADS 3, 4, or 5) requiring further testing, with no prior breast cancer history (Abnormal Screening Cohort) **You may NOT be eligible if...** - You have a personal history of breast cancer - You have already had a biopsy for a current abnormality (in the Abnormal Screening cohort) - You are pregnant - You are unable to provide a blood sample Talk to your doctor to see if this trial is right for you.