Investigate the Relationship Between Catastrophizing and the Perception of Itch Intensity in Healthy Individuals
Investigation of the Neurophysiological and Psychological Aspects of Itch
Aalborg University
46 participants
Apr 27, 2024
INTERVENTIONAL
Conditions
Summary
This project aims to investigate the relationship between different dimensions of catastrophizing (rumination, magnification, and helplessness) as well as some specific personality traits related to catastrophizing tendencies like anxiety sensitivity and fear sensitivity in the modulation of itch and pain intensities in an experimental setting.
Eligibility
Plain Language Summary
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Interventions
Histaminergic itch will be evoked by a 1% histamine solution. A droplet of histamine solution will be placed on the predetermined area on the forearm, and the SPT lancet will be pierced through the histamine with 120 g of pressure for 1-2 seconds.
25 spicules will be inserted in the center of the predefined skin area on the mandibular area. The spicules will be gently rubbed for 15-20 seconds in circular motion to facilitate epidermal penetration.
Locations(1)
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NCT06340438