RecruitingNot ApplicableNCT06340646

Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)


Sponsor

Washington University School of Medicine

Enrollment

990 participants

Start Date

Oct 18, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

The overall goal of the WU-PE-CGS is to build a rigorous, scientific evidence base for approaches that direct engagement of cancer patients and post-treatment cancer survivors as participants in cancer research, and to investigate the impact of directly engaging participants in decisions regarding returning of genomic results on participants' health and satisfaction. Participants in this study will be presented with the choice of types of genomic results to receive, and the Engagement Optimization Unit (EOU) will investigate the impact of this intervention on participant knowledge, expectations of benefit, personal utility, and decisional conflict.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This Washington University study collects tumor DNA and other biological samples from patients with specific cancer types to study the genetic drivers of their disease. The goal is to improve understanding of these cancers and help develop more targeted treatments. **You may be eligible if...** - You are 18 or older - You have been diagnosed with cholangiocarcinoma (bile duct cancer), multiple myeloma (blood cancer), or early-onset colon or rectal cancer - If you have multiple myeloma, you must identify as African American - If you have colon or rectal cancer, you must be African American AND were diagnosed at age 65 or younger - You are willing and able to sign the informed consent form **You may NOT be eligible if...** - You do not have one of the specified diagnoses - You do not meet the race/ethnicity or age-at-diagnosis requirements for myeloma or colorectal cancer - You are not willing or able to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERReturn of Genetic Results: Biomarker information from cancer cells

Participants will receive a novel return of results report that is tailored to their choices.

OTHERReturn of Genetic Results: Inherited mutations related to cancer

Participants will receive a novel return of results report that is tailored to their choices.

OTHERReturn of Genetic Results: Inherited mutations related to other medical issues

Participants will receive a novel return of results report that is tailored to their choices.


Locations(1)

Washington University School of Medicine

St Louis, Missouri, United States

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NCT06340646


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