An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

This study tests a new blood-based test using exosomes (tiny particles released by cells) to tell apart two types of primary liver cancer — hepatocellular carcinoma and cholangiocarcinoma — which currently can be difficult to distinguish without a biopsy. **You may be eligible if...** - You have been diagnosed with hepatocellular carcinoma (the most common liver cancer) or intrahepatic cholangiocarcinoma (bile duct cancer in the liver) - You have had standard diagnostic procedures and blood was drawn before any curative treatment began **You may NOT be eligible if...** - You have both types of liver cancer at the same time - Your liver cancer is not one of the two study types - Your cancer started somewhere else and spread to the liver (secondary cancer) - You are unable or unwilling to provide informed consent Talk to your doctor to see if this trial is right for you.