Primary Liver Cancer Clinical Trials

11 recruiting

Primary Liver Cancer Trials at a Glance

12 actively recruiting trials for primary liver cancer are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Chicago, New York, and Milan. Lead sponsors running primary liver cancer studies include City of Hope Medical Center, HistoSonics, Inc., and CNBG-Virogin Biotech (Shanghai) Ltd..

Browse primary liver cancer trials by phase

Treatments under study

About Primary Liver Cancer Clinical Trials

Looking for clinical trials for Primary Liver Cancer? There are currently 11 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Primary Liver Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Primary Liver Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting

Real-world Evaluation of the HistoSonics Edison System for Treatment of Liver Tumors Across Multidisciplinary Users (BOOMBOX: Master Study)

Liver NeoplasmsPrimary Liver CancerSecondary Liver Cancer+2 more
HistoSonics, Inc.5,000 enrolled27 locationsNCT06486454
Recruiting

An Exosome-Based Liquid Biopsy for the Differential Diagnosis of Primary Liver Cancer

CholangiocarcinomaHepatocellular CarcinomaHepatic Carcinoma+4 more
City of Hope Medical Center400 enrolled5 locationsNCT06342414
Recruiting

Optimizing Y90 Therapy for Radiation Lobectomy

Metastatic CancerHCCResection+2 more
Northwestern University104 enrolled2 locationsNCT04390724
Recruiting

cfDNA Methylation for Liver Cancer Recurrence Detection

Primary Liver Cancer
Wuhan Ammunition Life-tech Co., Ltd500 enrolled1 locationNCT07466602
Recruiting
Phase 2

Y-90 Treatment Response Using Transarterial Radioembolization

Liver CancerHepatocellular CarcinomaPrimary Liver Cancer+3 more
Thomas Jefferson University30 enrolled1 locationNCT07145801
Recruiting
Not Applicable

The Dragon PLC Trial (DRAGON-PLC)

CholangiocarcinomaHepatocellular Carcinoma (HCC)Primary Liver Cancer
Maastricht University358 enrolled55 locationsNCT06914648
Recruiting
Not Applicable

Stroke Volume Variation Versus Central Venous Pressure Guidance for Reducing Perioperative Blood Loss During Open Liver Resection

Primary Liver CancerLiver ResectionBenign Liver Tumor+2 more
Warangkana Lapisatepun74 enrolled1 locationNCT06905015
Recruiting
Phase 2

Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer

Primary Liver Cancer
Tianjin Medical University Cancer Institute and Hospital130 enrolled1 locationNCT06766643
Recruiting

Recurrent Liver Cancer: Reconceptualization and Reevaluation

Primary Liver CancerRecurrent Liver Cancer
Nanjing Medical University300 enrolled1 locationNCT06430983
Recruiting
Phase 1

Clinical Study of VG161 in Subjects with Advanced Primary Liver Cancer

Primary Liver Cancer
CNBG-Virogin Biotech (Shanghai) Ltd.44 enrolled1 locationNCT04806464
Recruiting

Liver Embolization Approaches for Tumor Management

CholangiocarcinomaHepatocellular CarcinomaMetastatic Cancer+4 more
IRCCS San Raffaele580 enrolled1 locationNCT05714124
Recruiting

Clinical Characteristics of Primary Liver Cancer

Primary Liver Cancer
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School1,000 enrolled1 locationNCT06325267