Application of tDCS Stimulation in Controlling Refractory Status Epilepticus
Application of Targeting Transcranial Direct Current Stimulation (tDCS) Stimulation in the Treatment of Refractory Status Epilepticus
Xuanwu Hospital, Beijing
32 participants
Apr 1, 2024
INTERVENTIONAL
Conditions
Summary
The purpose of the study is to assess the efficacy and safety of targeting tDCS stimulation for treatment of Refractory status epilepticus
Eligibility
Inclusion Criteria4
- Age between 14 and 80 year-old with Gender unlimited,
- Suitable for EEG monitoring;
- Clinical diagnosis of Refractory status epilepticus (status epilepticus that cannot be controlled by two types of antiepileptic drugs and at least one anesthetic);
- Informed consent to participate in this study was obtained from the participants or their surrogates
Exclusion Criteria4
- Unstable vital signs (systolic blood pressure\<90mmHg, heart rate\<60 beats/min, pulse oxygen saturation\<90%);
- Having severe skull injury/defect or medical equipment implanted in the head;
- Pregnancy;
- With any implantable electronic instrument (including pacemakers, vagus nerve stimulators) or metal implanted devices.
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Interventions
In the real-stimulation group, Treatment was for 20 min, repeated twice in a day, then again over the next few days. The maximum number of stimuli required to terminate the status epilepticus should not exceed 10. In the sham-stimulation group, The duration and frequency of tDCS are the same as those in the treatment group, but the tDCS device is not active during the 20 minutes of sham-stimulation
TDCS sham-stimulation
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06344338