RecruitingNot ApplicableNCT06345534

FAST-FORWARD vs HAI5

Randomized Comparison Between the FAST-FORWARD Schedule and the HAI5 Schedule for Breast Cancer Radiotherapy in 5 Fractions

Sponsor

University Hospital, Ghent

Enrollment

740 participants

Start Date

May 30, 2024

Study Type

INTERVENTIONAL

Conditions

Cancer, Breast

Summary

Randomized comparison between the FAST-FORWARD schedule and the HAI5 schedule for breast cancer radiotherapy in 5 fractions.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This trial compares two radiation treatment schedules for breast cancer after surgery. It tests a shorter, more intense course called FAST-FORWARD (5 treatments over 1 week) against a slightly longer schedule called HAI5 to find out which is better tolerated and equally effective. **You may be eligible if...** - You have been diagnosed with breast cancer - You are 18 or older (male or female) - You have already had breast-conserving surgery or a mastectomy with the goal of curing the cancer - Your medical team has recommended radiation therapy after surgery **You may NOT be eligible if...** - Your cancer has spread to other parts of the body - You have had radiation to the chest area before - Your surgical margins were not clear (cancer cells found at the edge of removed tissue) - You have had or are planning a breast reconstruction or implant - You need radiation to lymph nodes as well - You need radiation on both breasts Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEQuestionnaire

Patients will be asked to complete questionnaires at different times (before, during and after radiation) to evaluate which schedule gives the fewest side effects and the best quality of life. The basic questionnaire and questionnaire about early side effects will be completed weekly up to 6 weeks after radiotherapy. The questionnaire about late side effects will be completed: after 6 months, 1 year, 2 years, 3 years, 4 years and 5 years.