FAST-FORWARD vs HAI5
Randomized Comparison Between the FAST-FORWARD Schedule and the HAI5 Schedule for Breast Cancer Radiotherapy in 5 Fractions
University Hospital, Ghent
740 participants
May 30, 2024
INTERVENTIONAL
Conditions
Summary
Randomized comparison between the FAST-FORWARD schedule and the HAI5 schedule for breast cancer radiotherapy in 5 fractions.
Eligibility
Inclusion Criteria5
- histopathological diagnosis of breast cancer
- age 18 years or older
- male or female
- treated with breast conserving surgery or mastectomy with curative intent
- multidisciplinary decision of adjuvant radiotherapy after surgery
Exclusion Criteria9
- distant metastases
- decision of preoperative radiotherapy
- decision of partial breast irradiation
- positive resection margins ('ink on tumour')
- indication for boost on lymph node(s)
- history of thoracic or ipsilateral axillary radiotherapy (including radiotherapy of the contralateral breast or chest wall)
- need for bilateral irradiation
- breast reconstruction or expander
- patients unlikely to comply with the protocol (e.g. inability or unwillingness to complete the questionnaires at different time points).
Interventions
Patients will be asked to complete questionnaires at different times (before, during and after radiation) to evaluate which schedule gives the fewest side effects and the best quality of life. The basic questionnaire and questionnaire about early side effects will be completed weekly up to 6 weeks after radiotherapy. The questionnaire about late side effects will be completed: after 6 months, 1 year, 2 years, 3 years, 4 years and 5 years.
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT06345534