RecruitingNot ApplicableNCT06345872

Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain

SPIN Opioid: Improving Sleep and Reducing Opioid Use in Individuals With Chronic Pain


Sponsor

University of South Florida

Enrollment

165 participants

Start Date

Dec 11, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to test two behavioral interventions for chronic insomnia in individuals with chronic pain and use prescribed opioid medication to treat their chronic pain.


Eligibility

Min Age: 18 Years

Inclusion Criteria8

  • + yrs
  • willing to be randomized,
  • can read/understand English
  • diagnosed with chronic widespread pain and insomnia (as described below)
  • prescribed opioid medication for 1+ mo, 3+ times per week
  • desire to reduce or eliminate opioid use
  • written agreement from physician prescribing opioid medication
  • no prescribed or OTC sleep meds for 1+ mo, or stabilized on meds for 6+ wks

Exclusion Criteria14

  • unable to provide informed consent
  • cognitive impairment (MMSE <26)
  • sleep disorder other than insomnia \[i.e., sleep apnea (apnea/hypopnea index, AHI >15)
  • Periodic Limb Movement Disorder (myoclonus arousals per hour >15)\]
  • bipolar or seizure disorder (due to risk of sleep restriction treatment)
  • other severe, untreated major psychopathology except for depression or anxiety (e.g.,suicidal ideation/intent, psychotic disorders)
  • psychotropic or other medications (e.g., beta-blockers) that alter pain or sleep (medications prescribed for pain or sleep are allowed)
  • participation in other non-pharmacological treatment for pain, sleep, or mood outside the current trial
  • internal metal objects or electrical devices
  • pregnancy
  • presumptive/confirmed lumbar nerve root compression
  • confirmed lumbar spinal stenosis
  • <6 mos post-back surgery
  • other spinal disorders

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Interventions

BEHAVIORALCBT-I

Includes 8 weekly sessions of CBT-I and 2 bi-monthly boosters. Each session is to be completed individually by the participant in a single sitting (less than 45 mins). Each session should be completed in 7 days with next session released only after prior one completed.

BEHAVIORALTreatment as usual

Includes 8 weekly sessions of standard treatment and 2 bi-monthly boosters. Each session is to be completed individually by the participant in a single sitting (less than 45 mins). Each session should be completed in 7 days with next session released only after prior one completed.

OTHERTapered Withdrawal

Individualized gradual tapered withdrawal following CDC guidelines, additional check-ins and motivational interviewing with a therapist.


Locations(1)

University of South Florida

Tampa, Florida, United States

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NCT06345872


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