RecruitingNot ApplicableNCT06350227

Impact of Different Hemostasis Methods on Ovarian Function and Fertility During Laparoscopic Ovarian Cystectomy of Benign Ovarian Cyst


Sponsor

West China Second University Hospital

Enrollment

165 participants

Start Date

Apr 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare the impact of different hemostasis methods during laparoscopic ovarian cystectomy on ovarian function and fertility in women with benign ovarian cysts.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 40 Years

Inclusion Criteria7

  • Women diagnosed with benign ovarian cysts requiring surgical management.
  • Women who choose laparoscopic ovarian cystectomy voluntarily sign a surgical consent form.
  • Women participating in this study recognize three hemostatic methods and are ready to randomly accept one of them.
  • Women aged between 18 and 40 years old.
  • It was diagnosed by ultrasound as unilateral or bilateral benign ovarian cysts with a maximum diameter of 4-8cm. The nature of the cysts is ultimately confirmed by postoperative pathological examination.
  • Women with no previous history of ovarian surgery, chemotherapy, or pelvic radiation therapy.
  • Patients with no history of endocrine disorders such as hyperprolactinemia, hypothyroidism, or hyperthyroidism, and no history of endocrine therapy within 6 months before laparoscopic ovarian cystectomy.

Exclusion Criteria8

  • Polycystic ovary syndrome.
  • Pregnancy or lactation period.
  • Women with active pelvic inflammatory disease, genital or extragenital malignant tumors.
  • Women who have undergone two or more pelvic or abdominal surgeries.
  • Evidence of premature ovarian failure or premature menopause, such as AMH<1ng/ml.
  • Conversion to open surgery.
  • Women who refuse to sign informed consent or are unable to attend follow-up regularly.
  • Cysts that do not originate from the ovaries or have the characteristics of malignant tumors.

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Interventions

COMBINATION_PRODUCTthe absorbable hemostat and suture

The hemostasis method of the experimental group is to use both the absorbable hemostat and suture.

COMBINATION_PRODUCTelectrocoagulation and suture

The active comparator group is to use electrocoagulation and suture simultaneously to stop bleeding.

OTHERsuture

The placebo comparator is to use suture alone for hemostasis.


Locations(1)

West China Second University Hospital, Sichuan University

Chengdu, Sichuan, China

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NCT06350227


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