Reducing Fluid Overload in Heart Failure Patients Using a Non-invasive, Renal Independent System

This trial is testing a non-invasive device that removes excess fluid from the body — without using the kidneys — in heart failure patients who are retaining fluid (congestion) despite taking diuretic medications (water pills). Fluid overload is a common and dangerous problem in heart failure. **You may be eligible if...** - You are 21–79 years old - You have decompensated heart failure and/or chronic kidney disease (Stage 2 or higher) with significant fluid retention - You are not responding adequately to diuretics (at least 40 mg furosemide daily) - You have not been hospitalized for heart failure in the last 30 days - Your diuretic dose has not changed in the past 7 days - Your blood pressure is at least 100 mmHg systolic - Your NT-proBNP (a heart stress marker) is 600 pg/mL or above **You may NOT be eligible if...** - You have had a recent heart failure hospitalization in the past 30 days - Your blood pressure is too low - You are on dialysis or have end-stage kidney disease - You have had recent cardiac surgery or intervention Talk to your doctor to see if this trial is right for you.