RecruitingPhase 1NCT06362265

A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus

A Single Dose Study to Evaluate the Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus


Sponsor

Eli Lilly and Company

Enrollment

22 participants

Start Date

Oct 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The main purpose of this study is to evaluate how much of LY3209590 gets into the blood stream after a single dose and how long it takes the body to remove it in pediatric participants with Type 2 Diabetes Mellitus (T2DM). The study will last for approximately 100 days.


Eligibility

Min Age: 10 YearsMax Age: 17 Years

Plain Language Summary

Simplified for easier understanding

This study is testing how the body absorbs and processes a weekly insulin medication called LY3209590 in children and teenagers with Type 2 diabetes. **You may be eligible if...** - You have had Type 2 diabetes for at least 3 months - Your HbA1c (blood sugar average) is between 6.5% and 9.5% - Your BMI is 45 or below - You have never used insulin, or stopped insulin at least 3 months ago **You may NOT be eligible if...** - You had a severe low blood sugar episode in the past 6 months - You have kidney problems - You had a blood transfusion or major blood loss in the past 90 days - Your weight changed by 6% or more in the past 3 months - You have or had cancer - You are taking steroid medications (like prednisone) - You are in another clinical trial Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGLY3209590

Administered SC.


Locations(10)

NYU Langone

New York, New York, United States

Lifedoc Research - Lenox Park Drive

Memphis, Tennessee, United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

Johns Hopkins Hospital

Baltimore, Maryland, United States

Centricity Research Columbus Endocrinology

Columbus, Georgia, United States

UBMD Pediatrics

Buffalo, New York, United States

Joslin Diabetes Center

Boston, Massachusetts, United States

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, United States

Children's Hospital Los Angeles

Los Angeles, California, United States

Children's Healthcare of Atlanta - Center for Advanced Pediatrics

Atlanta, Georgia, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT06362265


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